Publications | International Center for Genetic Disease at Harvard Medical School

High neutrophil-to-lymphocyte ratio is associated with increased carotid artery intima-media thickness in type 2 diabetes.

Authors :Li X , Shen J , Lu Z , Chen M , Fang X , Wang G

Published On :2017 Jan

Journal Article

Abnormal Mechanisms of Plasticity and Metaplasticity in Autism Spectrum Disorders and Fragile X Syndrome.

Authors :Oberman LM , Ifert-Miller F , Najib U , Bashir S , Heydrich JG , Picker J , Rotenberg A , Pascual-Leone A

Published On :2016 Sep

Journal Article Research Support, N.I.H., Extramural

Comparison of Cas9 activators in multiple species.

Authors :Chavez A , Tuttle M , Pruitt BW , Ewen-Campen B , Chari R , Ter-Ovanesyan D , Haque SJ , Cecchi RJ , Kowal EJK , Buchthal J , Housden BE , Perrimon N , Collins JJ , Church G

Published On :2016 Jul

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Androgen-sensitive hypertension associated with soluble guanylate cyclase-α1 deficiency is mediated by 20-HETE.

Authors :Dordea AC , Vandenwijngaert S , Garcia V , Tainsh RE , Nathan DI , Allen K , Raher MJ , Tainsh LT , Zhang F , Lieb WS , Mikelman S , Kirby A , Stevens C , Thoonen R , Hindle AG , Sips PY , Falck JR , Daly MJ , Brouckaert P , Bloch KD , Bloch DB , Malhotra R , Schwartzman ML , Buys ES

Published On :2016 Jun 1

Journal Article

Selective solid-phase extraction of catecholamines from plasma using nanofibers doped with crown ether and their quantitation by HPLC with electrochemical detection.

Authors :Chen L , Zhu X , Shen J , Zhang W

Published On :2016 Jul

Evaluation Study Journal Article

Current and future prospects for hemophilia gene therapy.

Authors :Ward P , Walsh CE

Published On :2016 Jul

Journal Article Review

[Application of High-throughput Sequencing in Acute Myeloid Leukemia Patients with Positive FLT3-ITD].

Authors :Ma L , Jiang YW , Wang ST , Liu Q , Cong X , Shen J , Cao YY , Cao YT

Published On :2016 Apr

Journal Article

Characterization of Cas9-Guide RNA Orthologs.

Authors :Braff JL , Yaung SJ , Esvelt KM , Church GM

Published On :2016 May 2

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Characterizing Cas9 Protospacer-Adjacent Motifs with High-Throughput Sequencing of Library Depletion Experiments.

Authors :Braff JL , Yaung SJ , Esvelt KM , Church GM

Published On :2016 May 2

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

N-Acetylcysteine Therapy in an Infant with Transaldolase Deficiency Is Well Tolerated and Associated with Normalization of Alpha Fetoprotein Levels.

Authors :Rodan LH , Berry GT

Published On :2017

Journal Article

A Clinician's perspective on clinical exome sequencing.

Authors :O'Donnell-Luria AH , Miller DT

Published On :2016 Jun

Journal Article Review Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Current and future alternative therapies for beta-thalassemia major.

Authors :de Dreuzy E , Bhukhai K , Leboulch P , Payen E

Published On :2016 Feb

Journal Article Review

Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease.

Authors :Walker MA , Mohler KP , Hopkins KW , Oakley DH , Sweetser DA , Ibba M , Frosch MP , Thibert RL

Published On :2016 Aug

Case Reports Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, Non-U.S. Gov't

Scaling Pattern to Variations in Size during Development of the Vertebrate Neural Tube.

Authors :Uygur A , Young J , Huycke TR , Koska M , Briscoe J , Tabin CJ

Published On :2016 Apr 18

Journal Article Research Support, N.I.H., Extramural

Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array.

Authors :Fuller CW , Kumar S , Porel M , Chien M , Bibillo A , Stranges PB , Dorwart M , Tao C , Li Z , Guo W , Shi S , Korenblum D , Trans A , Aguirre A , Liu E , Harada ET , Pollard J , Bhat A , Cech C , Yang A , Arnold C , Palla M , Hovis J , Chen R , Morozova I , Kalachikov S , Russo JJ , Kasianowicz JJ , Davis R , Roever S , Church GM , Ju J

Published On :2016 May 10

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't