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MVGFormer: Multi-view perspective with graph-guided transformer for cryo-ET segmentation.

Authors :Li H , Li X , Wang H , Shi J , Chen H , Zhao Y , Du B , Barthelemy J , Kihara D , Shen J , Xu M
Published On :2026 Jan 3
Journal Article


Gene conversion is a key driver of diversity hotspots in M. tuberculosis antigens and virulence-associated loci.

Authors :Marin MG , Quinones-Olvera N , Jin H , Harris MA , Jeffrey BM , Rosenthal A , Murphy KC , Sassetti C , Li H , Farhat MR
Published On :2026 Mar 11
Journal Article Preprint


Mobile health application reduces dialysis catheter service time for patients with newly created arteriovenous fistulas.

Authors :Chen L , Hu Y , Zhang Y , Liu F , Fu Q , Shen J
Published On :2026
Journal Article


Biallelic variants in the noncoding RNA gene RNU4-2 cause a recessive neurodevelopmental syndrome with distinct white matter changes.

Authors :Rius R , Blakes AJM , Chen Y , De Jonghe J , Lecoquierre F , Dawes R , Cogne B , Kim HC , Alvi JR , Amblard F , Ansari M , Arlt A , Austin-Tse C , Baer S , Balasubramanian M , Balton EV , Barcia G , Beleza-Meireles A , Bernstein JA , Beygo J , Blanc P , Bramswig NC , Braun F , Buchzik D , Calame DG , Campbell J , Coutton C , Cunningham CA , Dargie N , Depienne C , Dipple KM , Dieux A , Dixit A , Dreyer L , Du H , El Chehadeh S , Field M , Ewans LJ , Geiger V , Gibbs RA , Glass I , Grunewald O , Gueguen P , Haack TB , Hadj Abdallah H , Harbuz R , Helbig I , Horvath J , Hustinx A , Isidor B , Jacquemont ML , Jamie F , Jeanne M , Kessler R , Klinkhammer H , Korenke GC , Kotzaeridou U , Krawitz P , Laurie S , Leventer RJ , Levy RJ , Lupski JR , Marijon P , McGinnis KE , Mendez R , Messaoud O , Nava C , Nizard M , O'Donnell-Luria A , O'Leary MC , Olivieri S , Parida A , Pehlivan D , Prentice AJ , Posey JE , Reuter CM , Satre V , Schluth-Bolard C , Smol T , Sultan T , Taylor J , Thauvin-Robinetvin C , Thevenon J , Uebergang E , Ueberberg S , Vincent-Delorme C , Wassmer E , Westwood E , Wheeler MT , Gulec EY , Vanderver A , Vossough A , Sanders SJ , Banka S , Findlay GM , MacArthur DG , Simons C , Whiffin N
Published On :2026 Apr 8
Journal Article


A Homozygous Nonsense Variant in the Oligosaccharyltransferase Complex Gene, RPN1, Causes a Congenital Disorder of Glycosylation.

Authors :Ng BG , Zhang W , Neil JE , Danish M , Marafi D , Kamal TM , Bastaki L , Al Saffar M , Yang E , He M , Walsh CA , Mochida GH , Freeze HH
Published On :2026 Apr 3
Journal Article


Histone Deacetylase 4: The Epigenetic Hub in Degenerative Musculoskeletal Diseases.

Authors :Huang J , Wang Z , Du G , Zhang Z , Zhang M , Feng Y , Tan Y , Zhao H , Zhang S , Xiong Y , Wang X , Shen J , Zhan H
Published On :2026 Mar 27
Journal Article


Futuristic global cell and gene therapy regulations based on a review of today's leading frameworks.

Authors :Hashmi SK , Jamil MA , de la Fuente J , Mahlangu J , Ozelo MC , Walters MC , Almannaei A , Srivastava A , Alzahrani H , Lu P , Kenet G , Nomura K , Leboulch P
Published On :2026 Jan 21
Journal Article Review


Integrating Ultrasound and Clinicopathologic Characteristics to Predict the Invasive Papillary Thyroid Carcinoma Among Indeterminate Thyroid Nodules.

Authors :Yao M , Zhang Z , Hua Z , Chen Y , Zhao S , Sun Y , Shen J , Zhang X
Published On :2026
Journal Article


Integrating 730,947 exome sequences with clinical literature improves gene discovery.

Authors :Guez J , Goodrich JK , Moldovan MA , Chao KR , Kar P , Panchal R , Wilson MW , Laricchia KM , Rohlicek G , Biba D , Marten D , He Q , Darnowsky PW , Grant R , Weisburd B , Baxter SM , Nadeau J , Lu W , Jahl S , Parsa S , Lamane A , DiTroia S , Fu J , Zhao X , Alarmani E , Tolonen C , Novod S , Bryant S , Stevens C , Chapman SB , Cusick C , Vittal C , Gauthier LD , Goldstein JI , Goldstein D , King D , Poterba T , Tiao G , gnomAD Project Consortium , Tranchero M , Lotter W , MacArthur DG , Brand H , Seplyarskiy V , Koch E , Talkowski ME , Solomonson M , Neale BM , O'Donnell-Luria A , Finucane HK , Sunyaev SR , Daly MJ , Rehm HL , Samocha KE , Karczewski KJ
Published On :2026 Mar 25
Journal Article Preprint


A platform to design and optimise fluorogenic scFvs for detection of interleukin 33.

Authors :Reese AE , Karmakar U , Restori M , Hermoso MA , Church GM , Kuru E , Vendrell M
Published On :2026 Mar 23
Journal Article


Co-delivery of cisplatin and Bmi1 siRNA via nanocapsules overcomes chemoresistance in ovarian cancer.

Authors :Liu M , Liu X , Heng J , Li C , Duan Y , Fu Q , Shen J , Zhang B , Zhang S , Xie Y
Published On :2026 Apr 1
Journal Article


Efficacy, Safety, and Population Pharmacokinetics of Eravacycline for Carbapenem-Resistant Organism Infections in Immunocompromised Hosts: A Multicenter Prospective Cohort Study.

Authors :Hou Y , Zhang L , Li H , Zhong L , Zhang H , Tang T , Zheng X , Zhou R , Lv S , Que Q , Tan B , Chen L , Hsu Y , Hu H , Shen J , Yue R , Chen K , Di W , Guo L , Chen L , Yu H , Huang X , Huang X , Pan C , Yang H , Pan L
Published On :2026 Mar 30
Journal Article


Systematic analysis of snRNA genes reveals frequent RNU2-2 variants in dominant and recessive developmental and epileptic encephalopathies.

Authors :Leitão E , Santini A , Cogne B , Essid M , Athanasiadou M , LaFlamme CW , Marijon P , Bernard V , Jousselin K , Chatron N , Barcia G , Keren B , Mignot C , Charles P , Besnard T , Paluch R , de Sainte Agathe JM , Almanza Fuerte EP , Sengupta S , Milh M , Ramond F , Allan T , An I , Araujo C , Arpin S , Austin-Tse C , Auvin S , Baer S , Bahi-Buisson N , Bak M , Barth M , Baulac S , Bednarek-Weirauch N , Begemann M , Bennett MF , Bensabath U , Bézieau S , Bhouri R , Biehler M , Hammer TB , Bogoin J , Bonanno E , Boussion S , Bris C , Brosseau-Beauvir A , Bruel AL , Briand-Suleau A , Buratti J , Celse T , Chambon P , Chemaly N , Chesneau B , Colin E , Colmard M , Colson C , Conrad S , Courtin T , Creveaux I , Cullier AC , Dang LT , de Saint Martin A , de Vanssay de Blavous Legendre C , Demeer B , Denommé-Pichon AS , Diekhoff P , DiTroia S , Doco-Fenzy M , Dubourg C , Dubucs C , Ducreux S , Dufour L , Duquet R , Durand B , El Chehadeh S , Elbracht M , Faivre L , Faoucher M , Faudet A , Forlani S , Fradin M , Gaignard P , Ganne B , Garde A , Géraud J , Gill D , Goldenberg A , Grabli D , Grisel C , Gueden S , Gueguen P , Guerrot AM , Guichet A , Haack TB , Härting N , Häusler MG , Heide S , Herget T , Héron B , Héron D , Herwig J , Heulin M , Holling T , Houdayer C , Isidor B , Jacquette A , Januel L , Jean-Marçais N , Kaiser FJ , Kaya S , King C , Konyukh M , Kraft F , Krause J , Kirstetter R , Kuechler A , Kurth I , Kutsche K , Labalme A , Laloy JS , Laugel V , Le Bricquir F , Lèbre AS , Lebrun M , Leguern E , Levy J , Lieffering N , Lyonnet S , Lüthy K , Macdonald SMW , Mansour-Hendili L , Maraval J , Marquardt I , Mattausch C , Mercier S , Messaoud O , Morel G , Mortreux J , Munnich A , Nabbout R , Nambot S , Navarro V , Neale A , Nguyen L , Nizon M , Nowak F , O'Leary MC , Odent S , Ojeda NM , Olin V , Olivieri S , Õunap K , Pais LS , Panagiotakaki E , Patat O , Perrin-Sabourin L , Petit F , Philippe C , Piton A , Planes M , Poirsier C , Pouzet A , Prouteau C , Quéméner-Redon S , Renaud M , Richard AC , Rio M , Rivier C , Robin-Renaldo F , Rollier P , Rossi M , Roubertie A , Ruault V , Rupin-Mas M , Saugier-Veber P , Saunier A , Saneto R , Sarrazin E , Sarret C , Schaefer E , Schluth-Bolard C , Schneider A , Schumann I , Seplyarskiy VB , Spranger S , Smol T , Sturm M , Sunyaev SR , Sperelakis-Beedham B , Stenton SL , Stock F , Tharreau M , Torun D , Toulouse J , Thiyagarajah H , Valence S , Valleix S , Van-Gils J , Villard L , Ville D , Villeneuve N , Vitobello A , Waernessyckle A , Wagner J , Weber Y , Wieczorek D , Witkowski T , Yadavilli M , Yammine T , Zaafrane-Khachnaoui K , Zaki MS , Ziegler A , Bramswig NC , Lermine A , Nicolas G , Gleeson JG , Sadleir LG , Hildebrand MS , Scheffer IE , Whiffin N , O'Donnell-Luria A , Mefford HC , Blanc P , Thevenon J , Charbonnier C , Charenton C , Depienne C , Lesca G , Nava C
Published On :2026 Mar 30
Journal Article


Deleterious coding variation associated with autism is shared across ancestries.

Authors :Natividad Avila M , Jung S , Satterstrom FK , Fu JM , Levy T , Sloofman LG , Klei L , Pichardo T , Marquez D , Stevens CR , Cusick CM , Ames JL , Campos GS , Cerros H , Chaskel R , Costa CIS , Cuccaro ML , Lopez ADP , Fernandez M , Ferro E , Galeano L , Girardi ACDES , Griswold AJ , Hernandez LC , Lourenço N , Ludena Y , Núñez-Ríos D , Oyama R , Peña KP , Pessah I , Schmidt R , Sweeney HM , Tolentino L , Wang JYT , Albores-Gallo L , Croen LA , Cruz-Fuentes CS , Hertz-Picciotto I , Kolevzon A , Lattig MC , Mayo L , Passos-Bueno MR , Pericak-Vance MA , Siper PM , Tassone F , Trelles MP , GALA Consortium , Autism Sequencing Consortium (ASC) , Talkowski ME , Daly MJ , Mahjani B , De Rubeis S , Cook EH , Roeder K , Betancur C , Devlin B , Buxbaum JD
Published On :2026 Mar 30
Journal Article


Incorporation of Clinical and Molecular Variant Properties Improves the Performance of in silico Pathogenicity Prediction Tools.

Authors :Isakov O , Fluss R , Marek-Yagel D , Sunyaev S , Ben-Shachar S
Published On :2026 Mar 25
Journal Article