Chief Executive and Director, Harvard Medical School International Center for Genetic Disease
Principal Investigator and Director, Bahrain National Genome Program at Harvard
Assistant Professor of Medicine, Harvard Medical School, and Brigham and Women's Hospital
Dr. Haghighi is a clinician-scientist in the Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. He is internationally recognized for his leadership in projects aimed at improving health and well-being worldwide. Dr. Haghighi regularly advises government leaders on national health policies and initiatives. He is an American Board-Certified Geneticist. He completed his graduate and clinical training at the University of Oxford, and Harvard Medical School.
Dr. Haghighi advises governments worldwide on developing national strategies for life sciences and AI and leads major national initiatives in population genomics and genomic medicine, helping countries translate the genetic diversity of their populations into advances in health, science, and innovation. These initiatives harness large-scale genomic and health data to advance precision medicine and disease prevention, accelerate drug discovery and AI development, and build enduring national capabilities in biomedical research and healthcare.
Dr. Haghighi’s research investigates the genetic basis of human disease, with a particular focus on cardiovascular diseases, and the translation of genomic discoveries into better diagnostics and patient care. He has served as Principal Investigator on NIH- and AHA-funded research investigating the genetics of unexplained cardiomyopathies in adults and children. Additionally, he is the Director of the GEnetics NEtwork in the Middle East and Africa (GENE-ME), a large clinical research network focused on discovering novel disease-causing variants and genotype-phenotype relationships while advancing genomic medicine and scientific capacity across the region.
Dr. Haghighi has led many international projects to advance medical science in different countries and improve the health and well-being of people. He is the Founding President of the Advancement Initiative for Medicine and Science (AIMS), a global foundation that brings together academics and physicians dedicated to advancing medical science and healthcare globally.
Among the many prestigious awards and honors, he has received for his scientific and international contributions are the Global Health Pioneer Award (for his pivotal role in enhancing the quality of life through innovative strategies and capacity-building initiatives), and the International Genetic Disorders Prevention Award (for his outstanding contributions to and scientific excellence in genetic research).
Chief Executive and Director, Harvard Medical School International Center for Genetic Disease
Principal Investigator and Director, Bahrain National Genome Program at Harvard
Assistant Professor of Medicine, Harvard Medical School, and Brigham and Women's Hospital
Dr. Haghighi is a clinician-scientist in the Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. He is internationally recognized for his leadership in projects aimed at improving health and well-being worldwide. Dr. Haghighi regularly advises government leaders on national health policies and initiatives. He is an American Board-Certified Geneticist. He completed his graduate and clinical training at the University of Oxford, and Harvard Medical School.
Dr. Haghighi advises governments worldwide on developing national strategies for life sciences and AI and leads major national initiatives in population genomics and genomic medicine, helping countries translate the genetic diversity of their populations into advances in health, science, and innovation. These initiatives harness large-scale genomic and health data to advance precision medicine and disease prevention, accelerate drug discovery and AI development, and build enduring national capabilities in biomedical research and healthcare.
Dr. Haghighi’s research investigates the genetic basis of human disease, with a particular focus on cardiovascular diseases, and the translation of genomic discoveries into better diagnostics and patient care. He has served as Principal Investigator on NIH- and AHA-funded research investigating the genetics of unexplained cardiomyopathies in adults and children. Additionally, he is the Director of the GEnetics NEtwork in the Middle East and Africa (GENE-ME), a large clinical research network focused on discovering novel disease-causing variants and genotype-phenotype relationships while advancing genomic medicine and scientific capacity across the region.
Dr. Haghighi has led many international projects to advance medical science in different countries and improve the health and well-being of people. He is the Founding President of the Advancement Initiative for Medicine and Science (AIMS), a global foundation that brings together academics and physicians dedicated to advancing medical science and healthcare globally.
Among the many prestigious awards and honors, he has received for his scientific and international contributions are the Global Health Pioneer Award (for his pivotal role in enhancing the quality of life through innovative strategies and capacity-building initiatives), and the International Genetic Disorders Prevention Award (for his outstanding contributions to and scientific excellence in genetic research).
Journal article
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Journal article
CONCLUSIONS: Melatonin supplementation may reduce fatigue in cancer patients, particularly at doses of 5-15 mg/day and with short-term use. Nonetheless, the certainty of evidence remains very low, highlighting the need for high-quality, large-scale RCTs with standardized methodologies to validate these results.