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Evan Koch

Ph.D.

Postdoctoral Research Fellow

Department of Biomedical Informatics, Harvard Medical School

Dr. Koch is a postdoctoral researcher in the Department of Biomedical Informatics at Harvard Medical School. He works on statistical and theoretical problems in population and evolutionary genetics. His current research projects include using precise mutation rate estimates in the human genome to measure natural selection on a fine scale, and the investigation of selection on human traits using the results of genome-wide association studies. He has also worked on arabidopsis and wolf genetics, and currently has added the SARS-CoV-2 virus to this mix. 

Dr. Koch obtained my PhD in Ecology and Evolution from the University of Chicago, where he was an NSF GRFP fellow. Before that, he graduated from the University of Texas with a BS in Biology (honors), and a certificate in computational science. 

Evan Koch

Ph.D.

Postdoctoral Research Fellow

Department of Biomedical Informatics, Harvard Medical School

Dr. Koch is a postdoctoral researcher in the Department of Biomedical Informatics at Harvard Medical School. He works on statistical and theoretical problems in population and evolutionary genetics. His current research projects include using precise mutation rate estimates in the human genome to measure natural selection on a fine scale, and the investigation of selection on human traits using the results of genome-wide association studies. He has also worked on arabidopsis and wolf genetics, and currently has added the SARS-CoV-2 virus to this mix. 

Dr. Koch obtained my PhD in Ecology and Evolution from the University of Chicago, where he was an NSF GRFP fellow. Before that, he graduated from the University of Texas with a BS in Biology (honors), and a certificate in computational science. 

Recent Publications

Effect and neurophysiological mechanisms of transcutaneous auricular vagus nerve stimulation (taVNS) for misophonia (taVNS-MISO): a study protocol for a single-centre double-blind randomised sham-controlled trial

Published On 2026 May 20

Journal article

INTRODUCTION: Misophonia is a newly recognised sound sensitivity disorder with clinically significant symptoms affecting up to 18% of the population. It is characterised by extreme negative reactions to specific sounds which are often repetitive and generated by the human oral-nasal tract (eg, sniffing and eating sounds). Although misophonia currently has no standard treatment, research suggests that transcutaneous auricular vagus nerve stimulation (taVNS) holds promise therapeutically. This...


Genetics of bipolar disorder: Translating discoveries to biological insights and clinical decision support

Published On 2026 May 07

Journal article

Bipolar disorder (BD) is a clinically heterogenous mental disorder with a diversity in clinical trajectories and treatment response. Twin studies have shown that BD is highly heritable, with estimates ranging from 60% to 90%. However, our understanding of this genetic component has yet to be translated into clinical interventions or prediction tools. In this review, we summarize findings from large-scale international collaborations, with the latest and largest study finding 298 genome-wide...