Share

Evan Koch

Ph.D.

Postdoctoral Research Fellow

Department of Biomedical Informatics, Harvard Medical School

Dr. Koch is a postdoctoral researcher in the Department of Biomedical Informatics at Harvard Medical School. He works on statistical and theoretical problems in population and evolutionary genetics. His current research projects include using precise mutation rate estimates in the human genome to measure natural selection on a fine scale, and the investigation of selection on human traits using the results of genome-wide association studies. He has also worked on arabidopsis and wolf genetics, and currently has added the SARS-CoV-2 virus to this mix. 

Dr. Koch obtained my PhD in Ecology and Evolution from the University of Chicago, where he was an NSF GRFP fellow. Before that, he graduated from the University of Texas with a BS in Biology (honors), and a certificate in computational science. 

Evan Koch

Ph.D.

Postdoctoral Research Fellow

Department of Biomedical Informatics, Harvard Medical School

Dr. Koch is a postdoctoral researcher in the Department of Biomedical Informatics at Harvard Medical School. He works on statistical and theoretical problems in population and evolutionary genetics. His current research projects include using precise mutation rate estimates in the human genome to measure natural selection on a fine scale, and the investigation of selection on human traits using the results of genome-wide association studies. He has also worked on arabidopsis and wolf genetics, and currently has added the SARS-CoV-2 virus to this mix. 

Dr. Koch obtained my PhD in Ecology and Evolution from the University of Chicago, where he was an NSF GRFP fellow. Before that, he graduated from the University of Texas with a BS in Biology (honors), and a certificate in computational science. 

Recent Publications

Demographic and Viral-Genetic Analyses of COVID-19 Severity in Bahrain Identify Local Risk Factors and a Protective Effect of Polymerase Mutations

Published On 2022 Aug 29

Journal article

A multitude of demographic, health, and genetic factors are associated with the risk of developing severe COVID-19 following infection by the SARS-CoV-2. There is a need to perform studies across human societies and to investigate the full spectrum of genetic variation of the virus. Using data from 869 COVID-19 patients in Bahrain between March 2020 and March 2021, we analyzed paired viral sequencing and non-genetic host data to understand host and viral determinants of severe COVID-19. We...


One-year results of minimally invasive fusion surgery of the sacroiliac joint as an alternative treatment after failed endoscopic thermal coagulation

Published On 2022 Mar 28

Journal article

CONCLUSION: The success of surgical intervention in 88% of the SIJ syndrome patients with inadequate results 12 months after thermocoagulation proves the superiority of SIJ fusion surgery. This study showed long-lasting pain relief by an average of 65% and a median improvement in functional impairments of 60%. In view of these results, fusion surgery should be considered for patients without sufficient success of thermocoagulation.