Clinical Director, Division of Cancer Genetics and Prevention
Senior Physician, Dana-Farber Cancer Institute
Assistant Professor of Medicine, Harvard Medical School
Huma Q. Rana, MD, MPH is the Clinical Director
of the Division of Cancer Genetics and Prevention at Dana-Farber Cancer
Institute, and Assistant Professor of Medicine at Harvard Medical School. At
Dana-Farber and its affiliates and satellites, Dr. Rana oversees the medical
management and the clinical operations that provide care to individuals with
rare genetic susceptibilities to cancer.
In addition to her clinical work, Dr. Rana leads
multiple clinical research projects focused on developing cancer prevention and
screening for those with hereditary cancer risk, and novel approaches to
improving access to cancer genetics services.
Dr. Rana received her medical degree from the Rutgers
Robert Wood Johnson Medical School, completed her residencies in Internal
Medicine and Clinical Genetics at the Icahn School of Medicine at Mount Sinai,
and received her MPH from the Harvard T.H. Chan School of Public Health. She has been a member of the Dana-Farber
faculty since 2012.
Clinical Director, Division of Cancer Genetics and Prevention
Senior Physician, Dana-Farber Cancer Institute
Assistant Professor of Medicine, Harvard Medical School
Huma Q. Rana, MD, MPH is the Clinical Director
of the Division of Cancer Genetics and Prevention at Dana-Farber Cancer
Institute, and Assistant Professor of Medicine at Harvard Medical School. At
Dana-Farber and its affiliates and satellites, Dr. Rana oversees the medical
management and the clinical operations that provide care to individuals with
rare genetic susceptibilities to cancer.
In addition to her clinical work, Dr. Rana leads
multiple clinical research projects focused on developing cancer prevention and
screening for those with hereditary cancer risk, and novel approaches to
improving access to cancer genetics services.
Dr. Rana received her medical degree from the Rutgers
Robert Wood Johnson Medical School, completed her residencies in Internal
Medicine and Clinical Genetics at the Icahn School of Medicine at Mount Sinai,
and received her MPH from the Harvard T.H. Chan School of Public Health. She has been a member of the Dana-Farber
faculty since 2012.
Journal article
Women diagnosed with fumarate hydratase (FH)-deficient uterine leiomyomata are at increased risk of renal cancer. This work suggests a more standardized pathology-genetic counseling referral pathway for these patients, and that research on underlying causes of FH-deficient uterine leiomyomata in the absence of germline FH pathogenic/likely pathogenic variants is needed.
Journal article
Standard methods of variant assessment in hereditary cancer susceptibility genes are limited by the lack of availability of key supporting evidence. In cancer, information derived from tumors can serve as a useful source in delineating the tumor behavior and the role of germline variants in tumor progression. We have previously demonstrated the value of integrating tumor and germline findings to comprehensively assess germline variants in hereditary cancer syndromes. Building on this work,...
