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Maha Farhat

M.D., M.Sc.

Assistant Professor of Biomedical Informatics

Harvard Medical School

Dr. Farhat is an Assistant Professor of of Biomedical Informatics atHarvard Medical School and a a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.

Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. Farhat's work has focused on bacterial and viral pathoges and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.

Maha Farhat holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. 

Maha Farhat

M.D., M.Sc.

Assistant Professor of Biomedical Informatics

Harvard Medical School

Dr. Farhat is an Assistant Professor of of Biomedical Informatics atHarvard Medical School and a a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.

Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. Farhat's work has focused on bacterial and viral pathoges and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.

Maha Farhat holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. 

Recent Publications

Pitfalls of bacterial pan-genome analysis approaches: a case study of M. tuberculosis and two less clonal bacterial species

Published On 2025 May 09

Journal article

Pan-genome analysis is a fundamental tool for studying bacterial genome evolution; however, the variety of methods used to define and measure the pan-genome poses challenges to the interpretation and reliability of results. Using Mycobacterium tuberculosis (Mtb)-characterized by clonal evolution, absence of horizontal gene transfer, and a small accessory genome-as a model system, we systematically evaluated sources of variability in pan-genome estimates. Our analysis revealed that differences in...


Genome-Wide Association Study Identifies a Locus at 17p13 to Be Associated With Intestinal Malrotation

Published On 2025 Apr 09

Journal article

CONCLUSION: We report results from the first GWAS on intestinal malrotation. A locus at 17p13 is associated with intestinal malrotation and may guide genetic guidance and improve our understanding of this malformation. Rs72631499 was found to be a binding site for HNF4A, a transcription factor that plays important roles in normal embryonic gut development.