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A machine learning decision support tool optimizes WGS utilization in a neonatal intensive care unit.

Authors :Juarez EF , Peterson B , Sanford Kobayashi E , Gilmer S , Tobin LE , Schultz B , Lenberg J , Carroll J , Bai-Tong S , Sweeney NM , Beebe C , Stewart L , Olsen L , Reinke J , Kiernan EA , Reimers R , Wigby K , Tackaberry C , Yandell M , Hobbs C , Bainbridge MN
Published On :2025 Jan 30
Journal Article


Randomizing the human genome by engineering recombination between repeat elements.

Authors :Koeppel J , Ferreira R , Vanderstichele T , Riedmayr LM , Peets EM , Girling G , Weller J , Murat P , Liberante FG , Ellis T , Church GM , Parts L
Published On :2025 Jan 31
Journal Article


The effects of the positioning of a bolt in the femoral neck system on the short-term outcomes of middle-aged and young adults with displaced femoral neck fractures.

Authors :Jin Y , Zhou X , Li Z , Liu Y , Xu R , Shen J , Zhang X , Yu X
Published On :2025 Jan 29
Journal Article


Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact.

Authors :Mondragon-Estrada E , Newburger JW , DePalma SR , Brueckner M , Cleveland J , Chung WK , Gelb BD , Goldmuntz E , Hagler DJ Jr , Huang H , McQuillen P , Miller TA , Panigrahy A , Porter GA Jr , Roberts AE , Rollins CK , Russell MW , Tristani-Firouzi M , Grant PE , Im K , Morton SU
Published On :2025 Feb 21
Journal Article


Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures.

Authors :Luna MJ , Oluoch PO , Miao J , Culviner P , Papavinasasundaram K , Jaecklein E , Shell SS , Ioerger TR , Fortune SM , Farhat MR , Sassetti CM
Published On :2025 Jan 28
Journal Article


Detailed tandem repeat allele profiling in 1,027 long-read genomes reveals genome-wide patterns of pathogenicity.

Authors :Danzi MC , Xu IRL , Fazal S , Dolzhenko E , Pellerin D , Weisburd B , Reuter C , Sampson J , Folland C , Wheeler M , O'Donnell-Luria A , Wuchty S , Ravenscroft G , Eberle MA , All of Us Research Program Long Read Working Group , Zuchner S
Published On :2025 Jan 20
Journal Article


Peganum harmala Polysaccharide Mitigates LPS-Induced Inflammatory Response in Macrophages by Activating Autophagy Pathway.

Authors :Rejiepu M , Shen J , Liang J , Maitikabili A , Yang J , Zhang L , Mi N
Published On :2025 Jan
Journal Article


Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection.

Authors :Negi S , Stenton SL , Berger SI , Canigiula P , McNulty B , Violich I , Gardner J , Hillaker T , O'Rourke SM , O'Leary MC , Carbonell E , Austin-Tse C , Lemire G , Serrano J , Mangilog B , VanNoy G , Kolmogorov M , Vilain E , O'Donnell-Luria A , Délot E , Miga KH , Monlong J , Paten B
Published On :2025 Feb 6
Journal Article


Missing Regulation Between Genetic Association and Transcriptional Abundance for Hypercholesterolemia Genes.

Authors :Hakim A , Connally NJ , Schnitzler GR , Cho MH , Jiang ZG , Sunyaev SR , Gupta RM
Published On :2025 Jan 15
Journal Article


Butyric Acid Modulates Gut Microbiota to Alleviate Inflammation and Secondary Bone Loss in Ankylosing Spondylitis.

Authors :You K , Yang L , Su Z , Shen J , Fan X , Guo Y , Yuan Z , Lu H
Published On :2024 Dec 24
Journal Article


Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course.

Authors :Urbut SM , Cho SMJ , Paruchuri K , Truong B , Haidermota S , Peloso G , Hornsby W , Philippakis A , Fahed AC , Natarajan P
Published On :2025 Jan 24
Journal Article


Rapid human oogonia-like cell specification via transcription factor-directed differentiation.

Authors :Pierson Smela M , Kramme CC , Fortuna PRJ , Wolf B , Goel S , Adams J , Ma C , Velychko S , Widocki U , Srikar Kavirayuni V , Chen T , Vincoff S , Dong E , Kohman RE , Kobayashi M , Shioda T , Church GM , Chatterjee P
Published On :2025 Jan 23
Journal Article


New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Study.

Authors :Liang J , Tang B , Shen J , Rejiepu M , Guo Y , Wang X , Shao S , Guo F , Wang Q , Zhang L
Published On :2025
Journal Article


Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.

Authors :Tavelli L , Nguyen T , Rodriguez MV , Mancini L , Giannobile WV , Barootchi S
Published On :2025 Jan 22
Journal Article


Melatonin lessens the susceptibility to atrial fibrillation in sleep deprivation by ameliorating Ca(2+) mishandling in response to mitochondrial oxidative stress.

Authors :Shen J , Liang J , Yuan P , Sun H , Rejiepu M , Guo F , Zhou X , Liu H , Zhang L , Tang B
Published On :2025 Feb 20
Journal Article