Share

How Will Machine Learning Inform the Clinical Care of Atrial Fibrillation?

Authors :Siontis KC , Yao X , Pirruccello JP , Philippakis AA , Noseworthy PA
Published On :2020 Jun 19
Journal Article Review


Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA.

Authors :Wang K , Lin RZ , Hong X , Ng AH , Lee CN , Neumeyer J , Wang G , Wang X , Ma M , Pu WT , Church GM , Melero-Martin JM
Published On :2020 Jul
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.

Authors :Shayota BJ , Donti TR , Xiao J , Gijavanekar C , Kennedy AD , Hubert L , Rodan L , Vanderpluym C , Nowak C , Bjornsson HT , Ganetzky R , Berry GT , Pappan KL , Sutton VR , Sun Q , Elsea SH
Published On :2020 Sep-Oct
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing.

Authors :MacKay MJ , Hooker AC , Afshinnekoo E , Salit M , Kelly J , Feldstein JV , Haft N , Schenkel D , Nambi S , Cai Y , Zhang F , Church G , Dai J , Wang CL , Levy S , Huber J , Ji HP , Kriegel A , Wyllie AL , Mason CE
Published On :2020 Sep
Letter Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.


Homozygous deletions implicate non-coding epigenetic marks in Autism spectrum disorder.

Authors :Schmitz-Abe K , Sanchez-Schmitz G , Doan RN , Hill RS , Chahrour MH , Mehta BK , Servattalab S , Ataman B , Lam AN , Morrow EM , Greenberg ME , Yu TW , Walsh CA , Markianos K
Published On :2020 Aug 20
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.

Authors :Fahed AC , Wang M , Homburger JR , Patel AP , Bick AG , Neben CL , Lai C , Brockman D , Philippakis A , Ellinor PT , Cassa CA , Lebo M , Ng K , Lander ES , Zhou AY , Kathiresan S , Khera AV
Published On :2020 Aug 20
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


APP gene copy number changes reflect exogenous contamination.

Authors :Kim J , Zhao B , Huang AY , Miller MB , Lodato MA , Walsh CA , Lee EA
Published On :2020 Aug
Letter Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Comment


De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease.

Authors :Boskovski MT , Homsy J , Nathan M , Sleeper LA , Morton S , Manheimer KB , Tai A , Gorham J , Lewis M , Swartz M , Alfieris GM , Bacha EA , Karimi M , Meyer D , Nguyen K , Bernstein D , Romano-Adesman A , Porter GA Jr , Goldmuntz E , Chung WK , Srivastava D , Kaltman JR , Tristani-Firouzi M , Lifton R , Roberts AE , Gaynor JW , Gelb BD , Kim R , Seidman JG , Brueckner M , Mayer JE Jr , Newburger JW , Seidman CE
Published On :2020 Aug
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Galactokinase deficiency: lessons from the GalNet registry.

Authors :Rubio-Gozalbo ME , Derks B , Das AM , Meyer U , Möslinger D , Couce ML , Empain A , Ficicioglu C , Juliá Palacios N , De Los Santos De Pelegrin MM , Rivera IA , Scholl-Bürgi S , Bosch AM , Cassiman D , Demirbas D , Gautschi M , Knerr I , Labrune P , Skouma A , Verloo P , Wortmann SB , Treacy EP , Timson DJ , Berry GT
Published On :2021 Jan
Journal Article Observational Study Research Support, Non-U.S. Gov't


Predicting functional effects of missense variants in voltage-gated sodium and calcium channels.

Authors :Heyne HO , Baez-Nieto D , Iqbal S , Palmer DS , Brunklaus A , May P , Epi25 Collaborative , Johannesen KM , Lauxmann S , Lemke JR , Møller RS , Pérez-Palma E , Scholl UI , Syrbe S , Lerche H , Lal D , Campbell AJ , Wang HR , Pan J , Daly MJ
Published On :2020 Aug 12
Journal Article Research Support, Non-U.S. Gov't


Paclitaxel Promotes Tumor-Infiltrating Macrophages in Breast Cancer.

Authors :Shen J , Chen C , Li Z , Hu S
Published On :2020 Jan-Dec
Journal Article Research Support, Non-U.S. Gov't


GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.

Authors :Zhou W , Brumpton B , Kabil O , Gudmundsson J , Thorleifsson G , Weinstock J , Zawistowski M , Nielsen JB , Chaker L , Medici M , Teumer A , Naitza S , Sanna S , Schultheiss UT , Cappola A , Karjalainen J , Kurki M , Oneka M , Taylor P , Fritsche LG , Graham SE , Wolford BN , Overton W , Rasheed H , Haug EB , Gabrielsen ME , Skogholt AH , Surakka I , Davey Smith G , Pandit A , Roychowdhury T , Hornsby WE , Jonasson JG , Senter L , Liyanarachchi S , Ringel MD , Xu L , Kiemeney LA , He H , Netea-Maier RT , Mayordomo JI , Plantinga TS , Hrafnkelsson J , Hjartarson H , Sturgis EM , Palotie A , Daly M , Citterio CE , Arvan P , Brummett CM , Boehnke M , de la Chapelle A , Stefansson K , Hveem K , Willer CJ , Åsvold BO
Published On :2020 Aug 7
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Korean Genome Project: 1094 Korean personal genomes with clinical information.

Authors :Jeon S , Bhak Y , Choi Y , Jeon Y , Kim S , Jang J , Jang J , Blazyte A , Kim C , Kim Y , Shim J , Kim N , Kim YJ , Park SG , Kim J , Cho YS , Park Y , Kim HM , Kim BC , Park NH , Shin ES , Kim BC , Bolser D , Manica A , Edwards JS , Church G , Lee S , Bhak J
Published On :2020 May
Journal Article Research Support, Non-U.S. Gov't



The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.

Authors :Kitamoto S , Nagao-Kitamoto H , Jiao Y , Gillilland MG 3rd , Hayashi A , Imai J , Sugihara K , Miyoshi M , Brazil JC , Kuffa P , Hill BD , Rizvi SM , Wen F , Bishu S , Inohara N , Eaton KA , Nusrat A , Lei YL , Giannobile WV , Kamada N
Published On :2020 Jul 23
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.