Publications | International Center for Genetic Disease at Harvard Medical School

Phenotypic Characterization of Individuals With Variants in Cardiovascular Genes in the Absence of a Primary Cardiovascular Indication for Testing.

Authors :Hylind RJ , Chandler SF , Beausejour Ladouceur V , Roberts AE , Bezzerides V , Christensen KD , Coggins M , Lakdawala NK , MacRae CA , Abrams DJ

Published On :2019 Mar

Letter Research Support, Non-U.S. Gov't

Relationship between metabolic syndrome and thyroid nodules and thyroid volume in an adult population.

Authors :Guo W , Tan L , Chen W , Fan L , Chen Y , Du C , Zhu M , Wei H , Wang W , Gao M , Cui T , Shen J , Zhang W

Published On :2019 Aug

Journal Article Research Support, Non-U.S. Gov't

'Fit-for-purpose?' - challenges and opportunities for applications of blockchain technology in the future of healthcare.

Authors :Mackey TK , Kuo TT , Gummadi B , Clauson KA , Church G , Grishin D , Obbad K , Barkovich R , Palombini M

Published On :2019 Mar 27

Journal Article Research Support, N.I.H., Extramural

Long non-coding RNA Taurine upregulated gene 1 promotes osteosarcoma cell metastasis by mediating HIF-1α via miR-143-5p.

Authors :Yu X , Hu L , Li S , Shen J , Wang D , Xu R , Yang H

Published On :2019 Mar 25

Journal Article

Antimicrobial resistance and molecular characterization of methicillin-resistant coagulase-negative staphylococci from public shared bicycles in Tianjin, China.

Authors :Xu Z , Liu S , Chen L , Liu Y , Tan L , Shen J , Zhang W

Published On :2019 Dec

Journal Article Research Support, Non-U.S. Gov't

FAM46C inhibits lipopolysaccharides-induced myocardial dysfunction via downregulating cellular adhesion molecules and inhibiting apoptosis.

Authors :Tan J , Sun T , Shen J , Zhu H , Gong Y , Zhu H , Wu G

Published On :2019 Jul 15

Journal Article

Atractylenolide II reverses the influence of lncRNA XIST/miR-30a-5p/ROR1 axis on chemo-resistance of colorectal cancer cells.

Authors :Zhang R , Wang Z , Yu Q , Shen J , He W , Zhou D , Yu Q , Fan J , Gao S , Duan L

Published On :2019 May

Journal Article Research Support, Non-U.S. Gov't

Accurate excited-state energetics by a combination of Monte Carlo sampling and equation-of-motion coupled-cluster computations.

Authors :Deustua JE , Yuwono SH , Shen J , Piecuch P

Published On :2019 Mar 21

Journal Article

Circular RNA expression alterations in colon tissues of Crohn's disease patients.

Authors :Qiao YQ , Cai CW , Shen J , Zheng Q , Ran ZH

Published On :2019 May

Journal Article

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies.

Authors :Sohail M , Maier RM , Ganna A , Bloemendal A , Martin AR , Turchin MC , Chiang CW , Hirschhorn J , Daly MJ , Patterson N , Neale B , Mathieson I , Reich D , Sunyaev SR

Published On :2019 Mar 21

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs.

Authors :DiStefano MT , Hemphill SE , Oza AM , Siegert RK , Grant AR , Hughes MY , Cushman BJ , Azaiez H , Booth KT , Chapin A , Duzkale H , Matsunaga T , Shen J , Zhang W , Kenna M , Schimmenti LA , Tekin M , Rehm HL , Tayoun ANA , Amr SS , ClinGen Hearing Loss Clinical Domain Working Group

Published On :2019 Oct

Journal Article Research Support, N.I.H., Extramural

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China.

Authors :Wang Q , Xiang J , Sun J , Yang Y , Guan J , Wang D , Song C , Guo L , Wang H , Chen Y , Leng J , Wang X , Zhang J , Han B , Zou J , Yan C , Zhao L , Luo H , Han Y , Yuan W , Zhang H , Wang W , Wang J , Yang H , Xu X , Yin Y , Morton CC , Zhao L , Zhu S , Shen J , Peng Z

Published On :2019 Oct

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Burden of unique and low prevalence somatic mutations correlates with cancer survival.

Authors :Klebanov N , Artomov M , Goggins WB , Daly E , Daly MJ , Tsao H

Published On :2019 Mar 19

Journal Article Research Support, N.I.H., Extramural

Linked-read analysis identifies mutations in single-cell DNA-sequencing data.

Authors :Bohrson CL , Barton AR , Lodato MA , Rodin RE , Luquette LJ , Viswanadham VV , Gulhan DC , Cortés-Ciriano I , Sherman MA , Kwon M , Coulter ME , Galor A , Walsh CA , Park PJ

Published On :2019 Apr

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Removal of the articular fibrous layers with discectomy leads to temporomandibular joint ankylosis.

Authors :Wang HL , Liu H , Shen J , Zhang PP , Liang SX , Yan YB

Published On :2019 May

Journal Article