Publications | International Center for Genetic Disease at Harvard Medical School

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.

Authors :Schoech AP , Jordan DM , Loh PR , Gazal S , O'Connor LJ , Balick DJ , Palamara PF , Finucane HK , Sunyaev SR , Price AL

Published On :2019 Feb 15

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Metagenomic study on the composition of culturable and non-culturable bacteria in tap water and biofilms at intensive care units.

Authors :Farhat M , Alkharsah KR , Alkhamis FI , Bukharie HA

Published On :2019 Feb

Journal Article

Results from a 78-week, single-arm, open-label phase 2 study to evaluate UX007 in pediatric and adult patients with severe long-chain fatty acid oxidation disorders (LC-FAOD).

Authors :Vockley J , Burton B , Berry GT , Longo N , Phillips J , Sanchez-Valle A , Tanpaiboon P , Grunewald S , Murphy E , Bowden A , Chen W , Chen CY , Cataldo J , Marsden D , Kakkis E

Published On :2019 Jan

Clinical Trial, Phase II Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Defining early hematopoietic-fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, activin, and BMP signaling.

Authors :Shen J , Lyu C , Zhu Y , Feng Z , Zhang S , Hoyle DL , Ji G , Brodsky RA , Cheng T , Wang ZZ

Published On :2019 Sep

Journal Article

Cerebral (18)F-FDG metabolism alteration in a neuropathic pain model following brachial plexus avulsion: A PET/CT study in rats.

Authors :Shen J , Huo BB , Hua XY , Zheng MX , Lu YC , Wu JJ , Shan CL , Xu JG

Published On :2019 Jun 1

Journal Article Research Support, Non-U.S. Gov't

Predicting Polygenic Risk of Psychiatric Disorders.

Authors :Martin AR , Daly MJ , Robinson EB , Hyman SE , Neale BM

Published On :2019 Jul 15

Journal Article Research Support, N.I.H., Extramural Review

Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index.

Authors :Wu H , Wu S , Zhu Y , Ye M , Shen J , Liu Y , Zhang Y , Bu S

Published On :2019 Feb 8

Journal Article Research Support, Non-U.S. Gov't

The Genetic Landscape of Diamond-Blackfan Anemia.

Authors :Ulirsch JC , Verboon JM , Kazerounian S , Guo MH , Yuan D , Ludwig LS , Handsaker RE , Abdulhay NJ , Fiorini C , Genovese G , Lim ET , Cheng A , Cummings BB , Chao KR , Beggs AH , Genetti CA , Sieff CA , Newburger PE , Niewiadomska E , Matysiak M , Vlachos A , Lipton JM , Atsidaftos E , Glader B , Narla A , Gleizes PE , O'Donohue MF , Montel-Lehry N , Amor DJ , McCarroll SA , O'Donnell-Luria AH , Gupta N , Gabriel SB , MacArthur DG , Lander ES , Lek M , Da Costa L , Nathan DG , Korostelev AA , Do R , Sankaran VG , Gazda HT

Published On :2019 Feb 7

Published Erratum