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CRISPR-Cas9 System: Opportunities and Concerns.

Authors :Vasiliou SK , Diamandis EP , Church GM , Greely HT , Baylis F , Thompson C , Schmitt-Ulms G
Published On :2016 Oct
Journal Article


Precision assessment of public attitudes toward genetic testing.

Authors :Shen J
Published On :2016 Dec
Journal Article


Design, synthesis, and testing toward a 57-codon genome.

Authors :Ostrov N , Landon M , Guell M , Kuznetsov G , Teramoto J , Cervantes N , Zhou M , Singh K , Napolitano MG , Moosburner M , Shrock E , Pruitt BW , Conway N , Goodman DB , Gardner CL , Tyree G , Gonzales A , Wanner BL , Norville JE , Lajoie MJ , Church GM
Published On :2016 Aug 19
Journal Article


HLA-DRB1 allele polymorphism and nasopharyngeal carcinoma risk: a meta-analysis.

Authors :Yao K , Yang S , Shen J , Zhang R , Li L
Published On :2017 Jan
Journal Article Meta-Analysis


Analysis of protein-coding genetic variation in 60,706 humans.

Authors :Lek M , Karczewski KJ , Minikel EV , Samocha KE , Banks E , Fennell T , O'Donnell-Luria AH , Ware JS , Hill AJ , Cummings BB , Tukiainen T , Birnbaum DP , Kosmicki JA , Duncan LE , Estrada K , Zhao F , Zou J , Pierce-Hoffman E , Berghout J , Cooper DN , Deflaux N , DePristo M , Do R , Flannick J , Fromer M , Gauthier L , Goldstein J , Gupta N , Howrigan D , Kiezun A , Kurki MI , Moonshine AL , Natarajan P , Orozco L , Peloso GM , Poplin R , Rivas MA , Ruano-Rubio V , Rose SA , Ruderfer DM , Shakir K , Stenson PD , Stevens C , Thomas BP , Tiao G , Tusie-Luna MT , Weisburd B , Won HH , Yu D , Altshuler DM , Ardissino D , Boehnke M , Danesh J , Donnelly S , Elosua R , Florez JC , Gabriel SB , Getz G , Glatt SJ , Hultman CM , Kathiresan S , Laakso M , McCarroll S , McCarthy MI , McGovern D , McPherson R , Neale BM , Palotie A , Purcell SM , Saleheen D , Scharf JM , Sklar P , Sullivan PF , Tuomilehto J , Tsuang MT , Watkins HC , Wilson JG , Daly MJ , MacArthur DG , Exome Aggregation Consortium
Published On :2016 Aug 18
Journal Article


Patterns of genic intolerance of rare copy number variation in 59,898 human exomes.

Authors :Ruderfer DM , Hamamsy T , Lek M , Karczewski KJ , Kavanagh D , Samocha KE , Exome Aggregation Consortium , Daly MJ , MacArthur DG , Fromer M , Purcell SM
Published On :2016 Oct
Journal Article


The burden of inhibitors in haemophilia patients.

Authors :Walsh CE , Jiménez-Yuste V , Auerswald G , Grancha S
Published On :2016 Aug 31
Journal Article


Alpha-Defensin 5 Expression is Regulated by microRNAs in the Caco-2 Intestinal Epithelial Cell Line.

Authors :Miles DR , Shen J , Chuang AY , Dong F , Wu F , Kwon J
Published On :2016 Apr
Journal Article


Susceptibility of field populations of the diamondback moth, Plutella xylostella, to a selection of insecticides in Central China.

Authors :Zhang S , Zhang X , Shen J , Mao K , You H , Li J
Published On :2016 Sep
Journal Article


A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Authors :Rivas MA , Graham D , Sulem P , Stevens C , Desch AN , Goyette P , Gudbjartsson D , Jonsdottir I , Thorsteinsdottir U , Degenhardt F , Mucha S , Kurki MI , Li D , D'Amato M , Annese V , Vermeire S , Weersma RK , Halfvarson J , Paavola-Sakki P , Lappalainen M , Lek M , Cummings B , Tukiainen T , Haritunians T , Halme L , Koskinen LL , Ananthakrishnan AN , Luo Y , Heap GA , Visschedijk MC , UK IBD Genetics Consortium , NIDDK IBD Genetics Consortium , MacArthur DG , Neale BM , Ahmad T , Anderson CA , Brant SR , Duerr RH , Silverberg MS , Cho JH , Palotie A , Saavalainen P , Kontula K , Färkkilä M , McGovern DP , Franke A , Stefansson K , Rioux JD , Xavier RJ , Daly MJ , Barrett J , de Lane K , Edwards C , Hart A , Hawkey C , Jostins L , Kennedy N , Lamb C , Lee J , Lees C , Mansfield J , Mathew C , Mowatt C , Newman B , Nimmo E , Parkes M , Pollard M , Prescott N , Randall J , Rice D , Satsangi J , Simmons A , Tremelling M , Uhlig H , Wilson D , Abraham C , Achkar JP , Bitton A , Boucher G , Croitoru K , Fleshner P , Glas J , Kugathasan S , Limbergen JV , Milgrom R , Proctor D , Regueiro M , Schumm PL , Sharma Y , Stempak JM , Targan SR , Wang MH
Published On :2016 Aug 9
Journal Article


Automatic segmentation of abdominal organs and adipose tissue compartments in water-fat MRI: Application to weight-loss in obesity.

Authors :Shen J , Baum T , Cordes C , Ott B , Skurk T , Kooijman H , Rummeny EJ , Hauner H , Menze BH , Karampinos DC
Published On :2016 Sep
Journal Article


A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition.

Authors :Li D , Achkar JP , Haritunians T , Jacobs JP , Hui KY , D'Amato M , Brand S , Radford-Smith G , Halfvarson J , Niess JH , Kugathasan S , Büning C , Schumm LP , Klei L , Ananthakrishnan A , Aumais G , Baidoo L , Dubinsky M , Fiocchi C , Glas J , Milgrom R , Proctor DD , Regueiro M , Simms LA , Stempak JM , Targan SR , Törkvist L , Sharma Y , Devlin B , Borneman J , Hakonarson H , Xavier RJ , Daly M , Brant SR , Rioux JD , Silverberg MS , Cho JH , Braun J , McGovern DP , Duerr RH
Published On :2016 Oct
Journal Article


Extra-articular distal tibia facture (AO-43A): A retrospective study comparing modified MIPPO with IMN.

Authors :Shen J , Xu J , Tang MJ , Luo CF , Zhang CQ
Published On :2016 Oct
Journal Article


TLE4 regulation of wnt-mediated inflammation underlies its role as a tumor suppressor in myeloid leukemia.

Authors :Shin TH , Brynczka C , Dayyani F , Rivera MN , Sweetser DA
Published On :2016 Sep
Journal Article