Publications | International Center for Genetic Disease at Harvard Medical School

New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Study.

Authors :Liang J , Tang B , Shen J , Rejiepu M , Guo Y , Wang X , Shao S , Guo F , Wang Q , Zhang L

Published On :2025

Journal Article

Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.

Authors :Tavelli L , Nguyen T , Rodriguez MV , Mancini L , Giannobile WV , Barootchi S

Published On :2025 Jan 22

Journal Article

Melatonin lessens the susceptibility to atrial fibrillation in sleep deprivation by ameliorating Ca(2+) mishandling in response to mitochondrial oxidative stress.

Authors :Shen J , Liang J , Yuan P , Sun H , Rejiepu M , Guo F , Zhou X , Liu H , Zhang L , Tang B

Published On :2025 Feb 20

Journal Article

All-Optical Modulation Photodetectors Based on the CdS/Graphene/Ge Sandwich Structures for Integrated Sensing-Computing.

Authors :Yang Q , Hu J , Li H , Du Q , Feng S , Yang D , Zhang Y , Shen J

Published On :2025 Mar

Journal Article

Species-specific Antimony Isotope Analysis by High Performance Liquid Chromatography Coupled with Multicollector ICPMS Using Hydride Generation as an Interface.

Authors :Chen L , Du Y , Li S , Liu X , Shen J , Zhu Z

Published On :2025 Feb 4

Journal Article

Enhanced detection of glutamate via transverse relaxation encoding with narrowband decoupling in the human brain.

Authors :An L , Hong S , Turon T , Pavletic A , Johnson CS , Derbyshire JA , Shen J

Published On :2025 Jun

Journal Article

Deleterious coding variation associated with autism is consistent across populations, as exemplified by admixed Latin American populations.

Authors :Avila MN , Jung S , Satterstrom FK , Fu JM , Levy T , Sloofman LG , Klei L , Pichardo T , Stevens CR , Cusick CM , Ames JL , Campos GS , Cerros H , Chaskel R , Costa CIS , Cuccaro ML , Del Pilar Lopez A , Fernandez M , Ferro E , Galeano L , Girardi ACDES , Griswold AJ , Hernandez LC , Lourenço N , Ludena Y , Nuñez DL , Oyama R , Peña KP , Pessah I , Schmidt R , Sweeney HM , Tolentino L , Wang JYT , Albores-Gallo L , Croen LA , Cruz-Fuentes CS , Hertz-Picciotto I , Kolevzon A , Lattig MC , Mayo L , Passos-Bueno MR , Pericak-Vance MA , Siper PM , Tassone F , Trelles MP , Autism Sequencing Consortium , Talkowski ME , Daly MJ , Mahjani B , De Rubeis S , Cook EH , Roeder K , Betancur C , Devlin B , Buxbaum JD

Published On :2025 Jan 6

Journal Article

NERINE reveals rare variant associations in gene networks across multiple phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease.

Authors :Nazeen S , Wang X , Morrow A , Strom R , Ethier E , Ritter D , Henderson A , Afroz J , Stitziel NO , Gupta RM , Luk K , Studer L , Khurana V , Sunyaev SR

Published On :2025 Jan 10

Journal Article

Inherent instability of simple DNA repeats shapes an evolutionarily stable distribution of repeat lengths.

Authors :McGinty RJ , Balick DJ , Mirkin SM , Sunyaev SR

Published On :2025 Jan 10

Journal Article

Lessons learned from 5 years of pegvaliase in US clinics: A case series.

Authors :Cooney E , Ammous Z , Bender T , Clague GE , Clifford M , Crutcher A , Davis-Keppen L , Havens K , Lah M , Sacharow S , Sanchez-Valle A , Vucko E , Wardley B , Wessenberg L , Andersson HC

Published On :2025 Mar

Journal Article

Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection.

Authors :Shen J , Li J , Shen Q , Hou J , Zhang C , Bai H , Ai X , Su Y , Wang Z , Zhang Y , Xu B , Hao J , Wang P , Zhang Q , Ye AY , Li Z , Feng T , Li L , Qi F , Wang Q , Sun Y , Liu C , Xi X , Yan L , Hong H , Chen Y , Xie X , Xie J , Liu X , Du R , Plebani R , Zhang L , Zhou D , Church G , Si L

Published On :2025 Feb

Journal Article

PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.

Authors :Zhang C , Hou J , Li Z , Shen Q , Bai H , Chen L , Shen J , Wang P , Su Y , Li J , Zhang Q , Liu C , Xi X , Qi F , Chen Y , Xie X , Ye AY , Liu X , Plebani R , Church G , Si L

Published On :2025 Sep

Journal Article

Clinical efficacy of pyrotinib combined with chemotherapy for neoadjuvant treatment in HER2-positive breast cancer: a single-center study.

Authors :Wei B , Yan H , Li F , Shen J

Published On :2025 Apr 1

Journal Article

Novel Immune Response Evasion Strategy to Redose Adeno-associated Viral Vectors and Prolong Survival in Surfactant Protein-B-Deficient Mice.

Authors :Kang MH , Thomas SP , Westley C , Blouin T , Xu L , Chan YK , Lisk E , Allen SE , Vadivel A , Nangle K , Ramamurthy J , Pei Y , Lewis LA , Chiang JJ , Romeo MJ , Vaena S , O'Quinn EC , Schrecker HD , Langdon CG , Nietert PJ , Church GM , Whitsett JA , Wootton SK , Thébaud B

Published On :2025 Jul

Journal Article

Transcriptome-wide outlier approach identifies individuals with minor spliceopathies.

Authors :Arriaga MT , Mendez R , Ungar RA , Bonner DE , Matalon DR , Lemire G , Goddard PC , Padhi EM , Miller AM , Nguyen JV , Ma J , Smith KS , Scott SA , Liao L , Ng Z , Marwaha S , Bademci G , Bivona SA , Tekin M , Undiagnosed Disease Network, Genomics Research to Elucidate the Genetics of Rare Diseases consortium , Bernstein JA , Montgomery SB , O'Donnell-Luria A , Wheeler MT , Ganesh VS

Published On :2025 Jan 3

Journal Article