Publications | International Center for Genetic Disease at Harvard Medical School

Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.

Authors :Madison AC , Royal MW , Vigneault F , Chen L , Griffin PB , Horowitz M , Church GM , Fair RB

Published On :2017 Sep 15

Journal Article

Fast computation of full density matrix of multispin systems for spatially localized in vivo magnetic resonance spectroscopy.

Authors :Zhang Y , An L , Shen J

Published On :2017 Aug

Journal Article

Millstone: software for multiplex microbial genome analysis and engineering.

Authors :Goodman DB , Kuznetsov G , Lajoie MJ , Ahern BW , Napolitano MG , Chen KY , Chen C , Church GM

Published On :2017 May 25

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Optimizing complex phenotypes through model-guided multiplex genome engineering.

Authors :Kuznetsov G , Goodman DB , Filsinger GT , Landon M , Rohland N , Aach J , Lajoie MJ , Church GM

Published On :2017 May 25

Journal Article

Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges.

Authors :Cai B , Li B , Kiga N , Thusberg J , Bergquist T , Chen YC , Niknafs N , Carter H , Tokheim C , Beleva-Guthrie V , Douville C , Bhattacharya R , Yeo HTG , Fan J , Sengupta S , Kim D , Cline M , Turner T , Diekhans M , Zaucha J , Pal LR , Cao C , Yu CH , Yin Y , Carraro M , Giollo M , Ferrari C , Leonardi E , Tosatto SCE , Bobe J , Ball M , Hoskins RA , Repo S , Church G , Brenner SE , Moult J , Gough J , Stanke M , Karchin R , Mooney SD

Published On :2017 Sep

Journal Article Research Support, N.I.H., Extramural

Gene Therapy in a Patient with Sickle Cell Disease.

Authors :Leboulch P , Cavazzana M

Published On :2017 May 25

Letter Comment

Using high-resolution variant frequencies to empower clinical genome interpretation.

Authors :Whiffin N , Minikel E , Walsh R , O'Donnell-Luria AH , Karczewski K , Ing AY , Barton PJR , Funke B , Cook SA , MacArthur D , Ware JS

Published On :2017 Oct

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Application of Zebrafish Models in Inflammatory Bowel Disease.

Authors :Hanyang L , Xuanzhe L , Xuyang C , Yujia Q , Jiarong F , Jun S , Zhihua R

Published On :2017

Journal Article Review

Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?

Authors :Walsh CT

Published On :2017 Jul 1

Journal Article Review

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

Authors :Weiner DJ , Wigdor EM , Ripke S , Walters RK , Kosmicki JA , Grove J , Samocha KE , Goldstein JI , Okbay A , Bybjerg-Grauholm J , Werge T , Hougaard DM , Taylor J , iPSYCH-Broad Autism Group , Psychiatric Genomics Consortium Autism Group , Skuse D , Devlin B , Anney R , Sanders SJ , Bishop S , Mortensen PB , Børglum AD , Smith GD , Daly MJ , Robinson EB

Published On :2017 Jul

Journal Article

Correction: Addressing the ethical issues raised by synthetic human entities with embryo-like features.

Authors :Aach J , Lunshof J , Iyer E , Church GM

Published On :2017 Apr 13

Journal Article Published Erratum

Addressing the ethical issues raised by synthetic human entities with embryo-like features.

Authors :Aach J , Lunshof J , Iyer E , Church GM

Published On :2017 Mar 21

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.

Authors :Duncan L , Yilmaz Z , Gaspar H , Walters R , Goldstein J , Anttila V , Bulik-Sullivan B , Ripke S , Eating Disorders Working Group of the Psychiatric Genomics Consortium , Thornton L , Hinney A , Daly M , Sullivan PF , Zeggini E , Breen G , Bulik CM

Published On :2017 Sep 1

Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Magnetic Cationic Amylose Nanoparticles Used to Deliver Survivin-Small Interfering RNA for Gene Therapy of Hepatocellular Carcinoma In Vitro.

Authors :Wu Z , Xu XL , Zhang JZ , Mao XH , Xie MW , Cheng ZL , Lu LJ , Duan XH , Zhang LM , Shen J

Published On :2017 May 11

Journal Article

Superparamagnetic Iron Oxide Nanoparticles-Complexed Cationic Amylose for In Vivo Magnetic Resonance Imaging Tracking of Transplanted Stem Cells in Stroke.

Authors :Lin BL , Zhang JZ , Lu LJ , Mao JJ , Cao MH , Mao XH , Zhang F , Duan XH , Zheng CS , Zhang LM , Shen J

Published On :2017 May 10

Journal Article