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Gene Therapy in a Patient with Sickle Cell Disease.

Authors :Leboulch P , Cavazzana M
Published On :2017 May 25
Letter Comment


Using high-resolution variant frequencies to empower clinical genome interpretation.

Authors :Whiffin N , Minikel E , Walsh R , O'Donnell-Luria AH , Karczewski K , Ing AY , Barton PJR , Funke B , Cook SA , MacArthur D , Ware JS
Published On :2017 Oct
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Application of Zebrafish Models in Inflammatory Bowel Disease.

Authors :Hanyang L , Xuanzhe L , Xuyang C , Yujia Q , Jiarong F , Jun S , Zhihua R
Published On :2017
Journal Article Review



Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

Authors :Weiner DJ , Wigdor EM , Ripke S , Walters RK , Kosmicki JA , Grove J , Samocha KE , Goldstein JI , Okbay A , Bybjerg-Grauholm J , Werge T , Hougaard DM , Taylor J , iPSYCH-Broad Autism Group , Psychiatric Genomics Consortium Autism Group , Skuse D , Devlin B , Anney R , Sanders SJ , Bishop S , Mortensen PB , Børglum AD , Smith GD , Daly MJ , Robinson EB
Published On :2017 Jul
Journal Article


Correction: Addressing the ethical issues raised by synthetic human entities with embryo-like features.

Authors :Aach J , Lunshof J , Iyer E , Church GM
Published On :2017 Apr 13
Journal Article Published Erratum


Addressing the ethical issues raised by synthetic human entities with embryo-like features.

Authors :Aach J , Lunshof J , Iyer E , Church GM
Published On :2017 Mar 21
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.

Authors :Duncan L , Yilmaz Z , Gaspar H , Walters R , Goldstein J , Anttila V , Bulik-Sullivan B , Ripke S , Eating Disorders Working Group of the Psychiatric Genomics Consortium , Thornton L , Hinney A , Daly M , Sullivan PF , Zeggini E , Breen G , Bulik CM
Published On :2017 Sep 1
Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Magnetic Cationic Amylose Nanoparticles Used to Deliver Survivin-Small Interfering RNA for Gene Therapy of Hepatocellular Carcinoma In Vitro.

Authors :Wu Z , Xu XL , Zhang JZ , Mao XH , Xie MW , Cheng ZL , Lu LJ , Duan XH , Zhang LM , Shen J
Published On :2017 May 11
Journal Article


Superparamagnetic Iron Oxide Nanoparticles-Complexed Cationic Amylose for In Vivo Magnetic Resonance Imaging Tracking of Transplanted Stem Cells in Stroke.

Authors :Lin BL , Zhang JZ , Lu LJ , Mao JJ , Cao MH , Mao XH , Zhang F , Duan XH , Zheng CS , Zhang LM , Shen J
Published On :2017 May 10
Journal Article


International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases.

Authors :Boycott KM , Rath A , Chong JX , Hartley T , Alkuraya FS , Baynam G , Brookes AJ , Brudno M , Carracedo A , den Dunnen JT , Dyke SOM , Estivill X , Goldblatt J , Gonthier C , Groft SC , Gut I , Hamosh A , Hieter P , Höhn S , Hurles ME , Kaufmann P , Knoppers BM , Krischer JP , Macek M Jr , Matthijs G , Olry A , Parker S , Paschall J , Philippakis AA , Rehm HL , Robinson PN , Sham PC , Stefanov R , Taruscio D , Unni D , Vanstone MR , Zhang F , Brunner H , Bamshad MJ , Lochmüller H
Published On :2017 May 4
Journal Article


Review of Salient Investigational Drugs for the Treatment of Fragile X Syndrome.

Authors :Munshi K , Pawlowski K , Gonzalez-Heydrich J , Picker JD
Published On :2017 Dec
Journal Article Review


Negative selection in humans and fruit flies involves synergistic epistasis.

Authors :Sohail M , Vakhrusheva OA , Sul JH , Pulit SL , Francioli LC , Genome of the Netherlands Consortium , Alzheimer’s Disease Neuroimaging Initiative , van den Berg LH , Veldink JH , de Bakker PIW , Bazykin GA , Kondrashov AS , Sunyaev SR
Published On :2017 May 5
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes.

Authors :Johnson MB , De Franco E , Lango Allen H , Al Senani A , Elbarbary N , Siklar Z , Berberoglu M , Imane Z , Haghighi A , Razavi Z , Ullah I , Alyaarubi S , Gardner D , Ellard S , Hattersley AT , Flanagan SE
Published On :2017 Aug
Journal Article Research Support, Non-U.S. Gov't


Relationship of Fibroblast Growth Factor 23 (FGF-23) Serum Levels With Low Bone Mass in Postmenopausal Women.

Authors :Shen J , Fu S , Song Y
Published On :2017 Dec
Clinical Trial Journal Article