Publications | International Center for Genetic Disease at Harvard Medical School

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex.

Authors :Johnson MB , Wang PP , Atabay KD , Murphy EA , Doan RN , Hecht JL , Walsh CA

Published On :2015 May

Journal Article

Highly efficient Cas9-mediated transcriptional programming.

Authors :Chavez A , Scheiman J , Vora S , Pruitt BW , Tuttle M , P R Iyer E , Lin S , Kiani S , Guzman CD , Wiegand DJ , Ter-Ovanesyan D , Braff JL , Davidsohn N , Housden BE , Perrimon N , Weiss R , Aach J , Collins JJ , Church GM

Published On :2015 Apr

Journal Article

Counterpoint: Risk factors, including genetic information, add value in stratifying patients for optimal preventive dental care.

Authors :Braun TM , Doucette-Stamm L , Duff GW , Kornman KS , Giannobile WV

Published On :2015 Mar

Journal Article

Genetic changes shaping the human brain.

Authors :Bae BI , Jayaraman D , Walsh CA

Published On :2015 Feb 23

Journal Article Review

Tissue engineering for bone regeneration and osseointegration in the oral cavity.

Authors :Pilipchuk SP , Plonka AB , Monje A , Taut AD , Lanis A , Kang B , Giannobile WV

Published On :2015 Apr

Journal Article Review

Cell-of-origin chromatin organization shapes the mutational landscape of cancer.

Authors :Polak P , Karlić R , Koren A , Thurman R , Sandstrom R , Lawrence M , Reynolds A , Rynes E , Vlahoviček K , Stamatoyannopoulos JA , Sunyaev SR

Published On :2015 Feb 19

Journal Article

Integrative analysis of 111 reference human epigenomes.

Authors :Roadmap Epigenomics Consortium , Kundaje A , Meuleman W , Ernst J , Bilenky M , Yen A , Heravi-Moussavi A , Kheradpour P , Zhang Z , Wang J , Ziller MJ , Amin V , Whitaker JW , Schultz MD , Ward LD , Sarkar A , Quon G , Sandstrom RS , Eaton ML , Wu YC , Pfenning AR , Wang X , Claussnitzer M , Liu Y , Coarfa C , Harris RA , Shoresh N , Epstein CB , Gjoneska E , Leung D , Xie W , Hawkins RD , Lister R , Hong C , Gascard P , Mungall AJ , Moore R , Chuah E , Tam A , Canfield TK , Hansen RS , Kaul R , Sabo PJ , Bansal MS , Carles A , Dixon JR , Farh KH , Feizi S , Karlic R , Kim AR , Kulkarni A , Li D , Lowdon R , Elliott G , Mercer TR , Neph SJ , Onuchic V , Polak P , Rajagopal N , Ray P , Sallari RC , Siebenthall KT , Sinnott-Armstrong NA , Stevens M , Thurman RE , Wu J , Zhang B , Zhou X , Beaudet AE , Boyer LA , De Jager PL , Farnham PJ , Fisher SJ , Haussler D , Jones SJ , Li W , Marra MA , McManus MT , Sunyaev S , Thomson JA , Tlsty TD , Tsai LH , Wang W , Waterland RA , Zhang MQ , Chadwick LH , Bernstein BE , Costello JF , Ecker JR , Hirst M , Meissner A , Milosavljevic A , Ren B , Stamatoyannopoulos JA , Wang T , Kellis M

Published On :2015 Feb 19

Journal Article

The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity.

Authors :Grimm DG , Azencott CA , Aicheler F , Gieraths U , MacArthur DG , Samocha KE , Cooper DN , Stenson PD , Daly MJ , Smoller JW , Duncan LE , Borgwardt KM

Published On :2015 May

Journal Article

A De Novo Variant in Galactose-1-P Uridylyltransferase (GALT) Leading to Classic Galactosemia.

Authors :Tran TT , Liu Y , Zwick ME , Ramachandran D , Cutler DJ , Huang X , Berry GT , Fridovich-Keil JL

Published On :2015

Journal Article

Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.

Authors :Lee JH , Daugharthy ER , Scheiman J , Kalhor R , Ferrante TC , Terry R , Turczyk BM , Yang JL , Lee HS , Aach J , Zhang K , Church GM

Published On :2015 Mar

Journal Article

Racial disparities in outcomes of adult heart transplantation.

Authors :Kilic A , Higgins RS , Whitson BA , Kilic A

Published On :2015 Mar 10

Journal Article Multicenter Study

Periodontal Health in Women With Early-Stage Postmenopausal Breast Cancer Newly on Aromatase Inhibitors: A Pilot Study.

Authors :Taichman LS , Inglehart MR , Giannobile WV , Braun T , Kolenic G , Van Poznak C

Published On :2015 Jul

Clinical Trial Journal Article

Silica-titania composite aerogel photocatalysts by chemical liquid deposition of titania onto nanoporous silica scaffolds.

Authors :Zu G , Shen J , Wang W , Zou L , Lian Y , Zhang Z

Published On :2015 Mar 11

Journal Article

De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes.

Authors :Gil-Rodríguez MC , Deardorff MA , Ansari M , Tan CA , Parenti I , Baquero-Montoya C , Ousager LB , Puisac B , Hernández-Marcos M , Teresa-Rodrigo ME , Marcos-Alcalde I , Wesselink JJ , Lusa-Bernal S , Bijlsma EK , Braunholz D , Bueno-Martinez I , Clark D , Cooper NS , Curry CJ , Fisher R , Fryer A , Ganesh J , Gervasini C , Gillessen-Kaesbach G , Guo Y , Hakonarson H , Hopkin RJ , Kaur M , Keating BJ , Kibaek M , Kinning E , Kleefstra T , Kline AD , Kuchinskaya E , Larizza L , Li YR , Liu X , Mariani M , Picker JD , Pié Á , Pozojevic J , Queralt E , Richer J , Roeder E , Sinha A , Scott RH , So J , Wusik KA , Wilson L , Zhang J , Gómez-Puertas P , Casale CH , Ström L , Selicorni A , Ramos FJ , Jackson LG , Krantz ID , Das S , Hennekam RC , Kaiser FJ , FitzPatrick DR , Pié J

Published On :2015 Apr

Journal Article Multicenter Study

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy.

Authors :Yuen M , Sandaradura SA , Dowling JJ , Kostyukova AS , Moroz N , Quinlan KG , Lehtokari VL , Ravenscroft G , Todd EJ , Ceyhan-Birsoy O , Gokhin DS , Maluenda J , Lek M , Nolent F , Pappas CT , Novak SM , D'Amico A , Malfatti E , Thomas BP , Gabriel SB , Gupta N , Daly MJ , Ilkovski B , Houweling PJ , Davidson AE , Swanson LC , Brownstein CA , Gupta VA , Medne L , Shannon P , Martin N , Bick DP , Flisberg A , Holmberg E , Van den Bergh P , Lapunzina P , Waddell LB , Sloboda DD , Bertini E , Chitayat D , Telfer WR , Laquerrière A , Gregorio CC , Ottenheijm CA , Bönnemann CG , Pelin K , Beggs AH , Hayashi YK , Romero NB , Laing NG , Nishino I , Wallgren-Pettersson C , Melki J , Fowler VM , MacArthur DG , North KN , Clarke NF

Published On :2015 Jan

Published Erratum