Publications | International Center for Genetic Disease at Harvard Medical School

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.

Authors :Lenz TL , Deutsch AJ , Han B , Hu X , Okada Y , Eyre S , Knapp M , Zhernakova A , Huizinga TW , Abecasis G , Becker J , Boeckxstaens GE , Chen WM , Franke A , Gladman DD , Gockel I , Gutierrez-Achury J , Martin J , Nair RP , Nöthen MM , Onengut-Gumuscu S , Rahman P , Rantapää-Dahlqvist S , Stuart PE , Tsoi LC , van Heel DA , Worthington J , Wouters MM , Klareskog L , Elder JT , Gregersen PK , Schumacher J , Rich SS , Wijmenga C , Sunyaev SR , de Bakker PI , Raychaudhuri S

Published On :2015 Sep

Journal Article

Analysis of small nucleolar RNAs in sputum for lung cancer diagnosis.

Authors :Su J , Liao J , Gao L , Shen J , Guarnera MA , Zhan M , Fang H , Stass SA , Jiang F

Published On :2016 Feb 2

Journal Article

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

Authors :Bhatt S , Gupta MK , Khamaisi M , Martinez R , Gritsenko MA , Wagner BK , Guye P , Busskamp V , Shirakawa J , Wu G , Liew CW , Clauss TR , Valdez I , El Ouaamari A , Dirice E , Takatani T , Keenan HA , Smith RD , Church G , Weiss R , Wagers AJ , Qian WJ , King GL , Kulkarni RN

Published On :2015 Aug 4

Journal Article

A novel 2q37 microdeletion containing human neural progenitors genes including STK25 results in severe developmental delay, epilepsy, and microcephaly.

Authors :Imitola J , Khurana DS , Teplyuk NM , Zucker M , Jethva R , Legido A , Krichevsky AM , Frangieh M , Walsh CA , Carvalho KS

Published On :2015 Nov

Journal Article

Mutations in ARID2 are associated with intellectual disabilities.

Authors :Shang L , Cho MT , Retterer K , Folk L , Humberson J , Rohena L , Sidhu A , Saliganan S , Iglesias A , Vitazka P , Juusola J , O'Donnell-Luria AH , Shen Y , Chung WK

Published On :2015 Oct

Journal Article

BIOSAFETY. Safeguarding gene drive experiments in the laboratory.

Authors :Akbari OS , Bellen HJ , Bier E , Bullock SL , Burt A , Church GM , Cook KR , Duchek P , Edwards OR , Esvelt KM , Gantz VM , Golic KG , Gratz SJ , Harrison MM , Hayes KR , James AA , Kaufman TC , Knoblich J , Malik HS , Matthews KA , O'Connor-Giles KM , Parks AL , Perrimon N , Port F , Russell S , Ueda R , Wildonger J

Published On :2015 Aug 28

Journal Article

The impact of Clostridum difficile on surgical rate among ulcerative colitis patients: A systemic review and meta-analysis.

Authors :Peng JC , Shen J , Zhu Q , Ran ZH

Published On :2015 Jul-Aug

Journal Article Meta-Analysis

Assessment of Thoracic Endografting Operative Mortality Risk Score: Development and Validation in 2,000 Patients.

Authors :Kilic A , Sultan IS , Arnaoutakis GJ , Higgins RS , Kilic A

Published On :2015 Sep

Journal Article

SHIELD: an integrative gene expression database for inner ear research.

Authors :Shen J , Scheffer DI , Kwan KY , Corey DP

Published On :2015

Journal Article

In Vitro Reconstitution of Metabolic Pathways: Insights into Nature's Chemical Logic.

Authors :Lowry B , Walsh CT , Khosla C

Published On :2015

Journal Article

Ulcerative Colitis Database: An Integrated Database and Toolkit for Gene Function and Medication Involved in Ulcerative Colitis.

Authors :Shen J , Mao AP , Zhu MM , Zhao P , Xu JJ , Zuo Z

Published On :2015 Aug

Journal Article

A genetic basis of variation in eccrine sweat gland and hair follicle density.

Authors :Kamberov YG , Karlsson EK , Kamberova GL , Lieberman DE , Sabeti PC , Morgan BA , Tabin CJ

Published On :2015 Aug 11

Journal Article

Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.

Authors :Kelsen JR , Dawany N , Moran CJ , Petersen BS , Sarmady M , Sasson A , Pauly-Hubbard H , Martinez A , Maurer K , Soong J , Rappaport E , Franke A , Keller A , Winter HS , Mamula P , Piccoli D , Artis D , Sonnenberg GF , Daly M , Sullivan KE , Baldassano RN , Devoto M

Published On :2015 Nov

Journal Article

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

Authors :Liu JZ , van Sommeren S , Huang H , Ng SC , Alberts R , Takahashi A , Ripke S , Lee JC , Jostins L , Shah T , Abedian S , Cheon JH , Cho J , Dayani NE , Franke L , Fuyuno Y , Hart A , Juyal RC , Juyal G , Kim WH , Morris AP , Poustchi H , Newman WG , Midha V , Orchard TR , Vahedi H , Sood A , Sung JY , Malekzadeh R , Westra HJ , Yamazaki K , Yang SK , International Multiple Sclerosis Genetics Consortium , International IBD Genetics Consortium , Barrett JC , Alizadeh BZ , Parkes M , Bk T , Daly MJ , Kubo M , Anderson CA , Weersma RK

Published On :2015 Sep

Journal Article Meta-Analysis

Puzzle Imaging: Using Large-Scale Dimensionality Reduction Algorithms for Localization.

Authors :Glaser JI , Zamft BM , Church GM , Kording KP

Published On :2015

Journal Article