Publications | International Center for Genetic Disease at Harvard Medical School

Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015.

Authors :Antman EM , Benjamin EJ , Harrington RA , Houser SR , Peterson ED , Bauman MA , Brown N , Bufalino V , Califf RM , Creager MA , Daugherty A , Demets DL , Dennis BP , Ebadollahi S , Jessup M , Lauer MS , Lo B , MacRae CA , McConnell MV , McCray AT , Mello MM , Mueller E , Newburger JW , Okun S , Packer M , Philippakis A , Ping P , Prasoon P , Roger VL , Singer S , Temple R , Turner MB , Vigilante K , Warner J , Wayte P , American Heart Association Data Sharing Summit Attendees

Published On :2015 Nov 5

Conference Proceedings

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles.

Authors :Prel A , Caval V , Gayon R , Ravassard P , Duthoit C , Payen E , Maouche-Chretien L , Creneguy A , Nguyen TH , Martin N , Piver E , Sevrain R , Lamouroux L , Leboulch P , Deschaseaux F , Bouillé P , Sensébé L , Pagès JC

Published On :2015

Journal Article

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions.

Authors :Kazanov MD , Roberts SA , Polak P , Stamatoyannopoulos J , Klimczak LJ , Gordenin DA , Sunyaev SR

Published On :2015 Nov 10

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Higher proliferation of peritumoral endothelial cells to IL-6/sIL-6R than tumoral endothelial cells in hepatocellular carcinoma.

Authors :Zhuang PY , Wang JD , Tang ZH , Zhou XP , Quan ZW , Liu YB , Shen J

Published On :2015 Nov 2

Journal Article Research Support, Non-U.S. Gov't

Spectral fitting using basis set modified by measured B0 field distribution.

Authors :Li N , An L , Shen J

Published On :2015 Dec

Journal Article Research Support, N.I.H., Intramural

An argument for early genomic sequencing in atypical cases: a WISP3 variant leads to diagnosis of progressive pseudorheumatoid arthropathy of childhood.

Authors :Cassa CA , Smith SE , Docken W , Hoffman E , McLaughlin H , Chun S , Leshchiner I , Miraoui H , Raychaudhuri S , Frank NY , Wilson BJ , Sunyaev SR , Maas RL , Brigham Genomic Medicine , Vuzman D

Published On :2016 Mar

Case Reports Letter Research Support, N.I.H., Extramural

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.

Authors :Cleynen I , Boucher G , Jostins L , Schumm LP , Zeissig S , Ahmad T , Andersen V , Andrews JM , Annese V , Brand S , Brant SR , Cho JH , Daly MJ , Dubinsky M , Duerr RH , Ferguson LR , Franke A , Gearry RB , Goyette P , Hakonarson H , Halfvarson J , Hov JR , Huang H , Kennedy NA , Kupcinskas L , Lawrance IC , Lee JC , Satsangi J , Schreiber S , Théâtre E , van der Meulen-de Jong AE , Weersma RK , Wilson DC , International Inflammatory Bowel Disease Genetics Consortium , Parkes M , Vermeire S , Rioux JD , Mansfield J , Silverberg MS , Radford-Smith G , McGovern DP , Barrett JC , Lees CW

Published On :2016 Jan 9

Journal Article Multicenter Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.

Authors :Cao Z , Conway KL , Heath RJ , Rush JS , Leshchiner ES , Ramirez-Ortiz ZG , Nedelsky NB , Huang H , Ng A , Gardet A , Cheng SC , Shamji AF , Rioux JD , Wijmenga C , Netea MG , Means TK , Daly MJ , Xavier RJ

Published On :2015 Oct 20

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing.

Authors :Tsioris K , Gupta NT , Ogunniyi AO , Zimnisky RM , Qian F , Yao Y , Wang X , Stern JN , Chari R , Briggs AW , Clouser CR , Vigneault F , Church GM , Garcia MN , Murray KO , Montgomery RR , Kleinstein SH , Love JC

Published On :2015 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A National Network of Neurotechnology Centers for the BRAIN Initiative.

Authors :Alivisatos AP , Chun M , Church GM , Greenspan RJ , Roukes ML , Yuste R

Published On :2015 Nov 4

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Taking a Deeper Look: The Promise of Regeneration in Periodontal Treatment.

Authors :Giannobile WV , McClain PK

Published On :2015 Apr

Journal Article

Novel loss-of-function variants in DIAPH1 associated with syndromic microcephaly, blindness, and early onset seizures.

Authors :Al-Maawali A , Barry BJ , Rajab A , El-Quessny M , Seman A , Coury SN , Barkovich AJ , Yang E , Walsh CA , Mochida GH , Stoler JM

Published On :2016 Feb

Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Lgr6 marks nail stem cells and is required for digit tip regeneration.

Authors :Lehoczky JA , Tabin CJ

Published On :2015 Oct 27

Journal Article Research Support, N.I.H., Extramural

Generation of gene-target dogs using CRISPR/Cas9 system.

Authors :Zou Q , Wang X , Liu Y , Ouyang Z , Long H , Wei S , Xin J , Zhao B , Lai S , Shen J , Ni Q , Yang H , Zhong H , Li L , Hu M , Zhang Q , Zhou Z , He J , Yan Q , Fan N , Zhao Y , Liu Z , Guo L , Huang J , Zhang G , Ying J , Lai L , Gao X

Published On :2015 Dec

Letter Research Support, Non-U.S. Gov't

Genome-wide inactivation of porcine endogenous retroviruses (PERVs).

Authors :Yang L , Güell M , Niu D , George H , Lesha E , Grishin D , Aach J , Shrock E , Xu W , Poci J , Cortazio R , Wilkinson RA , Fishman JA , Church G

Published On :2015 Nov 27

Journal Article Research Support, N.I.H., Extramural