Publications | International Center for Genetic Disease at Harvard Medical School

Replacement as an aging intervention.

Authors :Lore S , Poganik JR , Atala A , Church G , Gladyshev VN , Scheibye-Knudsen M , Verdin E

Published On :2025 May

Journal Article Review

FH Tumor Predisposition Syndrome.

Authors :Adam MP , Bick S , Mirzaa GM , Pagon RA , Wallace SE , Amemiya A , Kamihara J , Schultz KA , Rana HQ

Published On :1993

Review

Efficacy of botulinum neurotoxin-A in the treatment of neuropsychiatric symptoms in patients with Parkinson's disease: an open-label randomized controlled study.

Authors :Zhu X , Yang X , Wei M , Wang H , Shen J , Han Q

Published On :2025 Jun

Journal Article Randomized Controlled Trial

L-shaped association between serum klotho and prefrailty in physical frailty phenotype among adults in US: result from 2007 to 2016 National Health and Nutrition Examination Survey.

Authors :Xu M , Nie Z , Shen J , Xiao L , Hu X

Published On :2025 May 6

Journal Article

Consensus Report of the 20th European Workshop on Periodontology: Contemporary and Emerging Technologies in Periodontal Diagnosis.

Authors :Herrera D , Tonetti MS , Chapple I , Kebschull M , Papapanou PN , Sculean A , Abusleme L , Aimetti M , Belibasakis G , Blanco J , Bostanci N , Bouchard P , Buduneli N , Calciolari E , Carra MC , Chackartchi T , Dannewitz B , Danser M , Deng K , Derks J , Dietrich T , Discepoli N , Divaris K , Dommisch H , Donos N , Dutzan N , Eickholz P , Eren Kuru B , Faria Almeida R , Farina R , Feher B , Figuero E , Giannobile W , Gosset M , Graziani F , Gursoy UK , Hagenfeld D , Jepsen K , Jepsen S , Kumar P , Laine ML , Lambert F , Lang NP , Li Y , Loos B , Madianos P , Matesanz P , Mealey B , Molina A , Montero E , Nibali L , Preshaw P , Rakic M , Ramseier C , Salvi G , Sánchez N , Sanz-Sánchez I , Shapira L , Stavropoulos A , Tamimi F , Teughels W , Tomasi C , Trombelli L , Vassilopoulos S , Verket A , West N , Windisch P , Sanz M

Published On :2025 Aug

Journal Article Consensus Statement

Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma.

Authors :Rämö JT , Gorman BR , Weng LC , Jurgens SJ , Singhanetr P , Tieger MG , van Dijk EH , Halladay CW , Wang X , Hauser BM , Kim SH , Brinks J , Choi SH , Luo Y , FinnGen , VA Million Veteran Program , Pyarajan S , Nealon CL , Gorin MB , Wu WC , Anthony SA , Roncone DP , Sobrin L , Kaarniranta K , Yzer S , Palotie A , Peachey NS , Turunen JA , Boon CJ , Ellinor PT , Iyengar SK , Daly MJ , Rossin EJ

Published On :2025 May 3

Journal Article Meta-Analysis

A Novel Empirical Autoinduction Model to Characterize the Population Pharmacokinetics and Recommend Dose for Repotrectinib in Adult and Adolescents With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements.

Authors :Du S , Hu Z , Shen J , Hamuro L , Lam J , Lu M , Zhu L , Roy A , Kondic A

Published On :2025 Jul

Journal Article

Regulatable C-X-C chemokine receptor type 4 in iPSC-derived NK cells improves bone marrow chemotaxis and targeting resident tumor.

Authors :He X , Wang L , Zeng W , Wang Y , Chen N , Yang P , Ti A , Zhang Q , Shao Y , Wang M , Huang Z , Zhang X , Xu M , Liang L , Wang X , Ding X , Zhu T , Zhang P , Pan Z , Yang F , Zhou Y , Mo G , Hu J , Yue Y , Hu J , Deng Y , Ho T , Church GM , Hu Y , Huang H , Yang L

Published On :2025 Jul

Journal Article

Widespread recessive effects on common diseases in a cohort of 44,000 British Pakistanis and Bangladeshis with high autozygosity.

Authors :Heng TH , Walter K , Huang QQ , Karjalainen J , Daly MJ , Heyne HO , FinnGen , Malawsky DS , Kalantzis G , Genes & Health Research Team , Finer S , van Heel DA , Martin HC

Published On :2025 Jun 5

Journal Article

A call for built-in biosecurity safeguards for generative AI tools.

Authors :Wang M , Zhang Z , Bedi AS , Velasquez A , Guerra S , Lin-Gibson S , Cong L , Qu Y , Chakraborty S , Blewett M , Ma J , Xing E , Church G

Published On :2025 Jun

Letter

A Nomogram Prediction Model for Clinical Outcome of Trauma-induced Coagulopathy Patients with Severe Multiple Trauma.

Authors :Shen J , Xu F

Published On :2025 Jan-Mar

Journal Article

Advances in single-cell DNA sequencing enable insights into human somatic mosaicism.

Authors :Shao DD , Kriz AJ , Snellings DA , Zhou Z , Zhao Y , Enyenihi L , Walsh C

Published On :2025 Nov

Journal Article Review

Quality Indicators in Otolaryngology-Head and Neck Surgery: A Scoping Review.

Authors :Staibano P , Samargandy S , Cottrell J , Wang L , Au M , Gupta MK , Zhang H , Sommer DD , Walsh C , Monteiro E

Published On :2025 Jan-Dec

Journal Article Scoping Review

Development and psychometric validation of a patient-reported outcome measure scale for Crohn's disease anorectal stricture.

Authors :Li JR , Yang BL , Zhu ZX , Gong YX , Wang H , Gu YF , Zhang D , Xu MM , Jiang F , Kong J , Wang XP , Xu S , Wang C , Du P , Shen J , Mao R , Ke J , Tian F , Zhu WM , Zhu P

Published On :2025 May 8

Journal Article Validation Study

The diagnostic performance and reader agreement of the Prostate Imaging for Recurrence Reporting system in the evaluation of local recurrence in patients with biochemically recurrent prostate cancer.

Authors :Liu X , Yang S , Deng W , Li D , Shen J

Published On :2025 Sep

Journal Article