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Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants.

Authors :Bowers AA , Acker MG , Koglin A , Walsh CT
Published On :2010 Jun 2
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.


Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice.

Authors :Zhang G , Shi Q , Fahs SA , Kuether EL , Walsh CE , Montgomery RR
Published On :2010 Aug 26
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Fine mapping in 94 inbred mouse strains using a high-density haplotype resource.

Authors :Kirby A , Kang HM , Wade CM , Cotsapas C , Kostem E , Han B , Furlotte N , Kang EY , Rivas M , Bogue MA , Frazer KA , Johnson FM , Beilharz EJ , Cox DR , Eskin E , Daly MJ
Published On :2010 Jul
Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.


Developmental and degenerative features in a complicated spastic paraplegia.

Authors :Manzini MC , Rajab A , Maynard TM , Mochida GH , Tan WH , Nasir R , Hill RS , Gleason D , Al Saffar M , Partlow JN , Barry BJ , Vernon M , LaMantia AS , Walsh CA
Published On :2010 Apr
Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Clinical assessment incorporating a personal genome.

Authors :Ashley EA , Butte AJ , Wheeler MT , Chen R , Klein TE , Dewey FE , Dudley JT , Ormond KE , Pavlovic A , Morgan AA , Pushkarev D , Neff NF , Hudgins L , Gong L , Hodges LM , Berlin DS , Thorn CF , Sangkuhl K , Hebert JM , Woon M , Sagreiya H , Whaley R , Knowles JW , Chou MF , Thakuria JV , Rosenbaum AM , Zaranek AW , Church GM , Greely HT , Quake SR , Altman RB
Published On :2010 May 1
Journal Article Research Support, American Recovery and Reinvestment Act Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Angiogenic and osteogenic potential of bone repair cells for craniofacial regeneration.

Authors :Kaigler D , Pagni G , Park CH , Tarle SA , Bartel RL , Giannobile WV
Published On :2010 Sep
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


The apical complex couples cell fate and cell survival to cerebral cortical development.

Authors :Kim S , Lehtinen MK , Sessa A , Zappaterra MW , Cho SH , Gonzalez D , Boggan B , Austin CA , Wijnholds J , Gambello MJ , Malicki J , LaMantia AS , Broccoli V , Walsh CA
Published On :2010 Apr 15
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Human allelic variation: perspective from protein function, structure, and evolution.

Authors :Jordan DM , Ramensky VE , Sunyaev SR
Published On :2010 Jun
Journal Article Research Support, N.I.H., Extramural Review


Membrane properties of neuron-like cells generated from adult human bone-marrow-derived mesenchymal stem cells.

Authors :Fox LE , Shen J , Ma K , Liu Q , Shi G , Pappas GD , Qu T , Cheng J
Published On :2010 Dec
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis.

Authors :Zhang W , Bolla ML , Kahne D , Walsh CT
Published On :2010 May 12
Journal Article Research Support, N.I.H., Extramural


A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion.

Authors :Sommer MO , Church GM , Dantas G
Published On :2010 Apr 13
Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.



Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Authors :Neale BM , Fagerness J , Reynolds R , Sobrin L , Parker M , Raychaudhuri S , Tan PL , Oh EC , Merriam JE , Souied E , Bernstein PS , Li B , Frederick JM , Zhang K , Brantley MA Jr , Lee AY , Zack DJ , Campochiaro B , Campochiaro P , Ripke S , Smith RT , Barile GR , Katsanis N , Allikmets R , Daly MJ , Seddon JM
Published On :2010 Apr 20
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Regulation of reactive oxygen species by p53: implications for nitric oxide-mediated apoptosis.

Authors :Popowich DA , Vavra AK , Walsh CP , Bhikhapurwala HA , Rossi NB , Jiang Q , Aalami OO , Kibbe MR
Published On :2010 Jun
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Personal genomes in progress: from the human genome project to the personal genome project.

Authors :Lunshof JE , Bobe J , Aach J , Angrist M , Thakuria JV , Vorhaus DB , Hoehe MR , Church GM
Published On :2010
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