Publications | International Center for Genetic Disease at Harvard Medical School

Results of in utero atrial septoplasty in fetuses with hypoplastic left heart syndrome.

Authors :Marshall AC , Levine J , Morash D , Silva V , Lock JE , Benson CB , Wilkins-Haug LE , McElhinney DB , Tworetzky W

Published On :2008 Nov

Journal Article

The most conserved genome segments for life detection on Earth and other planets.

Authors :Isenbarger TA , Carr CE , Johnson SS , Finney M , Church GM , Gilbert W , Zuber MT , Ruvkun G

Published On :2008 Dec

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

Authors :Kuballa P , Huett A , Rioux JD , Daly MJ , Xavier RJ

Published On :2008

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an Fe(II)-dependent halogenase and a cyclopropane-forming flavoprotein.

Authors :Neumann CS , Walsh CT

Published On :2008 Oct 29

Journal Article Research Support, N.I.H., Extramural

Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly.

Authors :Heemstra JR Jr , Walsh CT

Published On :2008 Oct 29

Journal Article Research Support, N.I.H., Extramural

[Heavy metals in environmental media around drinking water conservation area of Shanghai].

Authors :Shi GT , Chen ZL , Zhang C , Bi CJ , Cheng C , Teng JY , Shen J , Wang DQ , Xu SY

Published On :2008 Jul

English Abstract Journal Article Research Support, Non-U.S. Gov't

beta-Hydroxylation of the aspartyl residue in the phytotoxin syringomycin E: characterization of two candidate hydroxylases AspH and SyrP in Pseudomonas syringae.

Authors :Singh GM , Fortin PD , Koglin A , Walsh CT

Published On :2008 Oct 28

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.

Authors :Lasky-Su J , Neale BM , Franke B , Anney RJ , Zhou K , Maller JB , Vasquez AA , Chen W , Asherson P , Buitelaar J , Banaschewski T , Ebstein R , Gill M , Miranda A , Mulas F , Oades RD , Roeyers H , Rothenberger A , Sergeant J , Sonuga-Barke E , Steinhausen HC , Taylor E , Daly M , Laird N , Lange C , Faraone SV

Published On :2008 Dec 5

Journal Article Research Support, N.I.H., Extramural

Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.

Authors :Snitkin ES , Dudley AM , Janse DM , Wong K , Church GM , Segrè D

Published On :2008

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Sequence analysis of P21-activated kinase 3 (PAK3) in chronic schizophrenia with cognitive impairment.

Authors :Morrow EM , Kane A , Goff DC , Walsh CA

Published On :2008 Dec

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.

Authors :Burkhardt R , Kenny EE , Lowe JK , Birkeland A , Josowitz R , Noel M , Salit J , Maller JB , Pe'er I , Daly MJ , Altshuler D , Stoffel M , Friedman JM , Breslow JL

Published On :2008 Nov

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

Authors :Raychaudhuri S , Remmers EF , Lee AT , Hackett R , Guiducci C , Burtt NP , Gianniny L , Korman BD , Padyukov L , Kurreeman FA , Chang M , Catanese JJ , Ding B , Wong S , van der Helm-van Mil AH , Neale BM , Coblyn J , Cui J , Tak PP , Wolbink GJ , Crusius JB , van der Horst-Bruinsma IE , Criswell LA , Amos CI , Seldin MF , Kastner DL , Ardlie KG , Alfredsson L , Costenbader KH , Altshuler D , Huizinga TW , Shadick NA , Weinblatt ME , de Vries N , Worthington J , Seielstad M , Toes RE , Karlson EW , Begovich AB , Klareskog L , Gregersen PK , Daly MJ , Plenge RM

Published On :2008 Oct

Comparative Study Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

MicroRNAs in the Hox network: an apparent link to posterior prevalence.

Authors :Yekta S , Tabin CJ , Bartel DP

Published On :2008 Oct

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.

Authors :Korn JM , Kuruvilla FG , McCarroll SA , Wysoker A , Nemesh J , Cawley S , Hubbell E , Veitch J , Collins PJ , Darvishi K , Lee C , Nizzari MM , Gabriel SB , Purcell S , Daly MJ , Altshuler D

Published On :2008 Oct

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Integrated detection and population-genetic analysis of SNPs and copy number variation.

Authors :McCarroll SA , Kuruvilla FG , Korn JM , Cawley S , Nemesh J , Wysoker A , Shapero MH , de Bakker PI , Maller JB , Kirby A , Elliott AL , Parkin M , Hubbell E , Webster T , Mei R , Veitch J , Collins PJ , Handsaker R , Lincoln S , Nizzari M , Blume J , Jones KW , Rava R , Daly MJ , Gabriel SB , Altshuler D

Published On :2008 Oct

Journal Article Research Support, Non-U.S. Gov't