Publications | International Center for Genetic Disease at Harvard Medical School

Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.

Authors :Burkhardt R , Kenny EE , Lowe JK , Birkeland A , Josowitz R , Noel M , Salit J , Maller JB , Pe'er I , Daly MJ , Altshuler D , Stoffel M , Friedman JM , Breslow JL

Published On :2008 Nov

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

Authors :Raychaudhuri S , Remmers EF , Lee AT , Hackett R , Guiducci C , Burtt NP , Gianniny L , Korman BD , Padyukov L , Kurreeman FA , Chang M , Catanese JJ , Ding B , Wong S , van der Helm-van Mil AH , Neale BM , Coblyn J , Cui J , Tak PP , Wolbink GJ , Crusius JB , van der Horst-Bruinsma IE , Criswell LA , Amos CI , Seldin MF , Kastner DL , Ardlie KG , Alfredsson L , Costenbader KH , Altshuler D , Huizinga TW , Shadick NA , Weinblatt ME , de Vries N , Worthington J , Seielstad M , Toes RE , Karlson EW , Begovich AB , Klareskog L , Gregersen PK , Daly MJ , Plenge RM

Published On :2008 Oct

Comparative Study Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

MicroRNAs in the Hox network: an apparent link to posterior prevalence.

Authors :Yekta S , Tabin CJ , Bartel DP

Published On :2008 Oct

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.

Authors :Korn JM , Kuruvilla FG , McCarroll SA , Wysoker A , Nemesh J , Cawley S , Hubbell E , Veitch J , Collins PJ , Darvishi K , Lee C , Nizzari MM , Gabriel SB , Purcell S , Daly MJ , Altshuler D

Published On :2008 Oct

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Integrated detection and population-genetic analysis of SNPs and copy number variation.

Authors :McCarroll SA , Kuruvilla FG , Korn JM , Cawley S , Nemesh J , Wysoker A , Shapero MH , de Bakker PI , Maller JB , Kirby A , Elliott AL , Parkin M , Hubbell E , Webster T , Mei R , Veitch J , Collins PJ , Handsaker R , Lincoln S , Nizzari M , Blume J , Jones KW , Rava R , Daly MJ , Gabriel SB , Altshuler D

Published On :2008 Oct

Journal Article Research Support, Non-U.S. Gov't

Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the action of the antibiotic.

Authors :Liu X , Fortin PD , Walsh CT

Published On :2008 Sep 9

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Determination of the glutamate-glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution.

Authors :Shen J , Rothman DL , Behar KL , Xu S

Published On :2009 Jan

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural

Host-response therapeutics for periodontal diseases.

Authors :Giannobile WV

Published On :2008 Aug

Journal Article Research Support, N.I.H., Extramural Review

Ethnically diverse causes of Walker-Warburg syndrome (WWS): FCMD mutations are a more common cause of WWS outside of the Middle East.

Authors :Manzini MC , Gleason D , Chang BS , Hill RS , Barry BJ , Partlow JN , Poduri A , Currier S , Galvin-Parton P , Shapiro LR , Schmidt K , Davis JG , Basel-Vanagaite L , Seidahmed MZ , Salih MA , Dobyns WB , Walsh CA

Published On :2008 Nov

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth.

Authors :Calderone CT , Bumpus SB , Kelleher NL , Walsh CT , Magarvey NA

Published On :2008 Sep 2

Journal Article Research Support, N.I.H., Extramural

Hippocrates revisited? Old ideals and new realities.

Authors :Lunshof JE , Chadwick R , Church GM

Published On :2008 Jan

Journal Article

Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate.

Authors :Comoy EE , Casalone C , Lescoutra-Etchegaray N , Zanusso G , Freire S , Marcé D , Auvré F , Ruchoux MM , Ferrari S , Monaco S , Salès N , Caramelli M , Leboulch P , Brown P , Lasmézas CI , Deslys JP

Published On :2008 Aug 20

Journal Article Research Support, Non-U.S. Gov't

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

Authors :Ferreira MA , O'Donovan MC , Meng YA , Jones IR , Ruderfer DM , Jones L , Fan J , Kirov G , Perlis RH , Green EK , Smoller JW , Grozeva D , Stone J , Nikolov I , Chambert K , Hamshere ML , Nimgaonkar VL , Moskvina V , Thase ME , Caesar S , Sachs GS , Franklin J , Gordon-Smith K , Ardlie KG , Gabriel SB , Fraser C , Blumenstiel B , Defelice M , Breen G , Gill M , Morris DW , Elkin A , Muir WJ , McGhee KA , Williamson R , MacIntyre DJ , MacLean AW , St CD , Robinson M , Van Beck M , Pereira AC , Kandaswamy R , McQuillin A , Collier DA , Bass NJ , Young AH , Lawrence J , Ferrier IN , Anjorin A , Farmer A , Curtis D , Scolnick EM , McGuffin P , Daly MJ , Corvin AP , Holmans PA , Blackwood DH , Gurling HM , Owen MJ , Purcell SM , Sklar P , Craddock N , Wellcome Trust Case Control Consortium

Published On :2008 Sep

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A latent oxazoline electrophile for N-O-C bond formation in pseudomonine biosynthesis.

Authors :Sattely ES , Walsh CT

Published On :2008 Sep 17

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Structural basis for the selectivity of the external thioesterase of the surfactin synthetase.

Authors :Koglin A , Löhr F , Bernhard F , Rogov VV , Frueh DP , Strieter ER , Mofid MR , Güntert P , Wagner G , Walsh CT , Marahiel MA , Dötsch V

Published On :2008 Aug 14

Journal Article Research Support, Non-U.S. Gov't