Publications | International Center for Genetic Disease at Harvard Medical School

[Comparison of effects between China made sirolimus-eluting stents and bare stents for treating patients with acute myocardial infarction].

Authors :Jin HG , Liu ZJ , Yang W , Wang WQ , Shi J , Wang DY , Wang ZH , Yu HM , Lai Y , Shen J , Fang P

Published On :2007 Aug

Comparative Study English Abstract Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy.

Authors :Desai S , Kyriakides T , Holodniy M , Al-Salman J , Griffith B , Kozal M

Published On :2007 Sep-Oct

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol.

Authors :Spirin V , Schmidt S , Pertsemlidis A , Cooper RS , Cohen JC , Sunyaev SR

Published On :2007 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Genome-wide detection and characterization of positive selection in human populations.

Authors :Sabeti PC , Varilly P , Fry B , Lohmueller J , Hostetter E , Cotsapas C , Xie X , Byrne EH , McCarroll SA , Gaudet R , Schaffner SF , Lander ES , International HapMap Consortium , Frazer KA , Ballinger DG , Cox DR , Hinds DA , Stuve LL , Gibbs RA , Belmont JW , Boudreau A , Hardenbol P , Leal SM , Pasternak S , Wheeler DA , Willis TD , Yu F , Yang H , Zeng C , Gao Y , Hu H , Hu W , Li C , Lin W , Liu S , Pan H , Tang X , Wang J , Wang W , Yu J , Zhang B , Zhang Q , Zhao H , Zhao H , Zhou J , Gabriel SB , Barry R , Blumenstiel B , Camargo A , Defelice M , Faggart M , Goyette M , Gupta S , Moore J , Nguyen H , Onofrio RC , Parkin M , Roy J , Stahl E , Winchester E , Ziaugra L , Altshuler D , Shen Y , Yao Z , Huang W , Chu X , He Y , Jin L , Liu Y , Shen Y , Sun W , Wang H , Wang Y , Wang Y , Xiong X , Xu L , Waye MM , Tsui SK , Xue H , Wong JT , Galver LM , Fan JB , Gunderson K , Murray SS , Oliphant AR , Chee MS , Montpetit A , Chagnon F , Ferretti V , Leboeuf M , Olivier JF , Phillips MS , Roumy S , Sallée C , Verner A , Hudson TJ , Kwok PY , Cai D , Koboldt DC , Miller RD , Pawlikowska L , Taillon-Miller P , Xiao M , Tsui LC , Mak W , Song YQ , Tam PK , Nakamura Y , Kawaguchi T , Kitamoto T , Morizono T , Nagashima A , Ohnishi Y , Sekine A , Tanaka T , Tsunoda T , Deloukas P , Bird CP , Delgado M , Dermitzakis ET , Gwilliam R , Hunt S , Morrison J , Powell D , Stranger BE , Whittaker P , Bentley DR , Daly MJ , de Bakker PI , Barrett J , Chretien YR , Maller J , McCarroll S , Patterson N , Pe'er I , Price A , Purcell S , Richter DJ , Sabeti P , Saxena R , Schaffner SF , Sham PC , Varilly P , Altshuler D , Stein LD , Krishnan L , Smith AV , Tello-Ruiz MK , Thorisson GA , Chakravarti A , Chen PE , Cutler DJ , Kashuk CS , Lin S , Abecasis GR , Guan W , Li Y , Munro HM , Qin ZS , Thomas DJ , McVean G , Auton A , Bottolo L , Cardin N , Eyheramendy S , Freeman C , Marchini J , Myers S , Spencer C , Stephens M , Donnelly P , Cardon LR , Clarke G , Evans DM , Morris AP , Weir BS , Tsunoda T , Johnson TA , Mullikin JC , Sherry ST , Feolo M , Skol A , Zhang H , Zeng C , Zhao H , Matsuda I , Fukushima Y , Macer DR , Suda E , Rotimi CN , Adebamowo CA , Ajayi I , Aniagwu T , Marshall PA , Nkwodimmah C , Royal CD , Leppert MF , Dixon M , Peiffer A , Qiu R , Kent A , Kato K , Niikawa N , Adewole IF , Knoppers BM , Foster MW , Clayton EW , Watkin J , Gibbs RA , Belmont JW , Muzny D , Nazareth L , Sodergren E , Weinstock GM , Wheeler DA , Yakub I , Gabriel SB , Onofrio RC , Richter DJ , Ziaugra L , Birren BW , Daly MJ , Altshuler D , Wilson RK , Fulton LL , Rogers J , Burton J , Carter NP , Clee CM , Griffiths M , Jones MC , McLay K , Plumb RW , Ross MT , Sims SK , Willey DL , Chen Z , Han H , Kang L , Godbout M , Wallenburg JC , L'Archevêque P , Bellemare G , Saeki K , Wang H , An D , Fu H , Li Q , Wang Z , Wang R , Holden AL , Brooks LD , McEwen JE , Guyer MS , Wang VO , Peterson JL , Shi M , Spiegel J , Sung LM , Zacharia LF , Collins FS , Kennedy K , Jamieson R , Stewart J

Published On :2007 Oct 18

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A second generation human haplotype map of over 3.1 million SNPs.

Authors :International HapMap Consortium , Frazer KA , Ballinger DG , Cox DR , Hinds DA , Stuve LL , Gibbs RA , Belmont JW , Boudreau A , Hardenbol P , Leal SM , Pasternak S , Wheeler DA , Willis TD , Yu F , Yang H , Zeng C , Gao Y , Hu H , Hu W , Li C , Lin W , Liu S , Pan H , Tang X , Wang J , Wang W , Yu J , Zhang B , Zhang Q , Zhao H , Zhao H , Zhou J , Gabriel SB , Barry R , Blumenstiel B , Camargo A , Defelice M , Faggart M , Goyette M , Gupta S , Moore J , Nguyen H , Onofrio RC , Parkin M , Roy J , Stahl E , Winchester E , Ziaugra L , Altshuler D , Shen Y , Yao Z , Huang W , Chu X , He Y , Jin L , Liu Y , Shen Y , Sun W , Wang H , Wang Y , Wang Y , Xiong X , Xu L , Waye MM , Tsui SK , Xue H , Wong JT , Galver LM , Fan JB , Gunderson K , Murray SS , Oliphant AR , Chee MS , Montpetit A , Chagnon F , Ferretti V , Leboeuf M , Olivier JF , Phillips MS , Roumy S , Sallée C , Verner A , Hudson TJ , Kwok PY , Cai D , Koboldt DC , Miller RD , Pawlikowska L , Taillon-Miller P , Xiao M , Tsui LC , Mak W , Song YQ , Tam PK , Nakamura Y , Kawaguchi T , Kitamoto T , Morizono T , Nagashima A , Ohnishi Y , Sekine A , Tanaka T , Tsunoda T , Deloukas P , Bird CP , Delgado M , Dermitzakis ET , Gwilliam R , Hunt S , Morrison J , Powell D , Stranger BE , Whittaker P , Bentley DR , Daly MJ , de Bakker PI , Barrett J , Chretien YR , Maller J , McCarroll S , Patterson N , Pe'er I , Price A , Purcell S , Richter DJ , Sabeti P , Saxena R , Schaffner SF , Sham PC , Varilly P , Altshuler D , Stein LD , Krishnan L , Smith AV , Tello-Ruiz MK , Thorisson GA , Chakravarti A , Chen PE , Cutler DJ , Kashuk CS , Lin S , Abecasis GR , Guan W , Li Y , Munro HM , Qin ZS , Thomas DJ , McVean G , Auton A , Bottolo L , Cardin N , Eyheramendy S , Freeman C , Marchini J , Myers S , Spencer C , Stephens M , Donnelly P , Cardon LR , Clarke G , Evans DM , Morris AP , Weir BS , Tsunoda T , Mullikin JC , Sherry ST , Feolo M , Skol A , Zhang H , Zeng C , Zhao H , Matsuda I , Fukushima Y , Macer DR , Suda E , Rotimi CN , Adebamowo CA , Ajayi I , Aniagwu T , Marshall PA , Nkwodimmah C , Royal CD , Leppert MF , Dixon M , Peiffer A , Qiu R , Kent A , Kato K , Niikawa N , Adewole IF , Knoppers BM , Foster MW , Clayton EW , Watkin J , Gibbs RA , Belmont JW , Muzny D , Nazareth L , Sodergren E , Weinstock GM , Wheeler DA , Yakub I , Gabriel SB , Onofrio RC , Richter DJ , Ziaugra L , Birren BW , Daly MJ , Altshuler D , Wilson RK , Fulton LL , Rogers J , Burton J , Carter NP , Clee CM , Griffiths M , Jones MC , McLay K , Plumb RW , Ross MT , Sims SK , Willey DL , Chen Z , Han H , Kang L , Godbout M , Wallenburg JC , L'Archevêque P , Bellemare G , Saeki K , Wang H , An D , Fu H , Li Q , Wang Z , Wang R , Holden AL , Brooks LD , McEwen JE , Guyer MS , Wang VO , Peterson JL , Shi M , Spiegel J , Sung LM , Zacharia LF , Collins FS , Kennedy K , Jamieson R , Stewart J

Published On :2007 Oct 18

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Cloning and characterization of the biosynthetic gene cluster for kutznerides.

Authors :Fujimori DG , Hrvatin S , Neumann CS , Strieker M , Marahiel MA , Walsh CT

Published On :2007 Oct 16

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces.

Authors :Fujimori DG , Barr EW , Matthews ML , Koch GM , Yonce JR , Walsh CT , Bollinger JM Jr , Krebs C , Riggs-Gelasco PJ

Published On :2007 Nov 7

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Ube3a mRNA and protein expression are not decreased in Mecp2R168X mutant mice.

Authors :Lawson-Yuen A , Liu D , Han L , Jiang ZI , Tsai GE , Basu AC , Picker J , Feng J , Coyle JT

Published On :2007 Nov 14

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Multiplex amplification of large sets of human exons.

Authors :Porreca GJ , Zhang K , Li JB , Xie B , Austin D , Vassallo SL , LeProust EM , Peck BJ , Emig CJ , Dahl F , Gao Y , Church GM , Shendure J

Published On :2007 Nov

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Effect of adjunctive systemic azithromycin with periodontal surgery in the treatment of chronic periodontitis in smokers: a pilot study.

Authors :Dastoor SF , Travan S , Neiva RF , Rayburn LA , Giannobile WV , Wang HL

Published On :2007 Oct

Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Development of a focused oligonucleotide-array comparative genomic hybridization chip for clinical diagnosis of genomic imbalance.

Authors :Shen Y , Irons M , Miller DT , Cheung SW , Lip V , Sheng X , Tomaszewicz K , Shao H , Fang H , Tang HS , Irons M , Walsh CA , Platt O , Gusella JF , Wu BL

Published On :2007 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Validation Study