Publications | International Center for Genetic Disease at Harvard Medical School

Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid.

Authors :Howard-Jones AR , Walsh CT

Published On :2006 Sep 20

Journal Article Research Support, N.I.H., Extramural

The role of RELN in lissencephaly and neuropsychiatric disease.

Authors :Chang BS , Duzcan F , Kim S , Cinbis M , Aggarwal A , Apse KA , Ozdel O , Atmaca M , Zencir S , Bagci H , Walsh CA

Published On :2007 Jan 5

Case Reports Comparative Study Journal Article Research Support, N.I.H., Extramural

Growth factor delivery for oral and periodontal tissue engineering.

Authors :Kaigler D , Cirelli JA , Giannobile WV

Published On :2006 Sep

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

An efficient implementation of the "cluster-in-molecule" approach for local electron correlation calculations.

Authors :Li S , Shen J , Li W , Jiang Y

Published On :2006 Aug 21

Journal Article

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration.

Authors :Maller J , George S , Purcell S , Fagerness J , Altshuler D , Daly MJ , Seddon JM

Published On :2006 Sep

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Interdomain communication between the thiolation and thioesterase domains of EntF explored by combinatorial mutagenesis and selection.

Authors :Zhou Z , Lai JR , Walsh CT

Published On :2006 Aug

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Aneurysm syndromes caused by mutations in the TGF-beta receptor.

Authors :Loeys BL , Schwarze U , Holm T , Callewaert BL , Thomas GH , Pannu H , De Backer JF , Oswald GL , Symoens S , Manouvrier S , Roberts AE , Faravelli F , Greco MA , Pyeritz RE , Milewicz DM , Coucke PJ , Cameron DE , Braverman AC , Byers PH , De Paepe AM , Dietz HC

Published On :2006 Aug 24

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection.

Authors :Lai JR , Fischbach MA , Liu DR , Walsh CT

Published On :2006 Aug 30

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Towards synthesis of a minimal cell.

Authors :Forster AC , Church GM

Published On :2006

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Review

Double-chambered right ventricle in an adult with Noonan syndrome.

Authors :Patel AM , Kim JB , Roberts AE , Aragam J

Published On :2006 Sep-Oct

Case Reports Journal Article

Electrical remodeling in a canine model of ischemic cardiomyopathy.

Authors :Liu XS , Jiang M , Zhang M , Tang D , Clemo HF , Higgins RS , Tseng GN

Published On :2007 Jan

Journal Article Research Support, N.I.H., Extramural

Development of heart valves requires Gata4 expression in endothelial-derived cells.

Authors :Rivera-Feliciano J , Lee KH , Kong SW , Rajagopal S , Ma Q , Springer Z , Izumo S , Tabin CJ , Pu WT

Published On :2006 Sep

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Characterization of the cereulide NRPS alpha-hydroxy acid specifying modules: activation of alpha-keto acids and chiral reduction on the assembly line.

Authors :Magarvey NA , Ehling-Schulz M , Walsh CT

Published On :2006 Aug 23

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

Authors :Fischbach MA , Walsh CT

Published On :2006 Aug

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Nature's inventory of halogenation catalysts: oxidative strategies predominate.

Authors :Vaillancourt FH , Yeh E , Vosburg DA , Garneau-Tsodikova S , Walsh CT

Published On :2006 Aug

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review