Publications | International Center for Genetic Disease at Harvard Medical School

Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination.

Authors :Totsugawa T , Yong C , Rivas-Carrillo JD , Soto-Gutierrez A , Navarro-Alvarez N , Noguchi H , Okitsu T , Westerman KA , Kohara M , Reth M , Tanaka N , Leboulch P , Kobayashi N

Published On :2007 Jul

Journal Article

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Authors :Graham RR , Kyogoku C , Sigurdsson S , Vlasova IA , Davies LR , Baechler EC , Plenge RM , Koeuth T , Ortmann WA , Hom G , Bauer JW , Gillett C , Burtt N , Cunninghame Graham DS , Onofrio R , Petri M , Gunnarsson I , Svenungsson E , Rönnblom L , Nordmark G , Gregersen PK , Moser K , Gaffney PM , Criswell LA , Vyse TJ , Syvänen AC , Bohjanen PR , Daly MJ , Behrens TW , Altshuler D

Published On :2007 Apr 17

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Both doublecortin and doublecortin-like kinase play a role in cortical interneuron migration.

Authors :Friocourt G , Liu JS , Antypa M , Rakic S , Walsh CA , Parnavelas JG

Published On :2007 Apr 4

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Site-specific protein labeling by Sfp phosphopantetheinyl transferase.

Authors :Yin J , Lin AJ , Golan DE , Walsh CT

Published On :2006

Journal Article

Retroperitoneal liposarcoma: MR characteristics and pathological correlative analysis.

Authors :Song T , Shen J , Liang BL , Mai WW , Li Y , Guo HC

Published On :2007 Sep-Oct

Journal Article

Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display.

Authors :Yin J , Straight PD , Hrvatin S , Dorrestein PC , Bumpus SB , Jao C , Kelleher NL , Kolter R , Walsh CT

Published On :2007 Mar

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

BluB cannibalizes flavin to form the lower ligand of vitamin B12.

Authors :Taga ME , Larsen NA , Howard-Jones AR , Walsh CT , Walker GC

Published On :2007 Mar 22

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Microfluidic immunoassays as rapid saliva-based clinical diagnostics.

Authors :Herr AE , Hatch AV , Throckmorton DJ , Tran HM , Brennan JS , Giannobile WV , Singh AK

Published On :2007 Mar 27

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Ascertainment through family history of disease often decreases the power of family-based association studies.

Authors :Ferreira MA , Sham P , Daly MJ , Purcell S

Published On :2007 Jul

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Medical sequencing at the extremes of human body mass.

Authors :Ahituv N , Kavaslar N , Schackwitz W , Ustaszewska A , Martin J , Hebert S , Doelle H , Ersoy B , Kryukov G , Schmidt S , Yosef N , Ruppin E , Sharan R , Vaisse C , Sunyaev S , Dent R , Cohen J , McPherson R , Pennacchio LA

Published On :2007 Apr

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Most rare missense alleles are deleterious in humans: implications for complex disease and association studies.

Authors :Kryukov GV , Pennacchio LA , Sunyaev SR

Published On :2007 Apr

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts.

Authors :de Magalhães JP , Costa J , Church GM

Published On :2007 Feb

Journal Article Research Support, N.I.H., Extramural

Actinobacillus actinomycetemcomitans lipopolysaccharide-mediated experimental bone loss model for aggressive periodontitis.

Authors :Rogers JE , Li F , Coatney DD , Rossa C , Bronson P , Krieder JM , Giannobile WV , Kirkwood KL

Published On :2007 Mar

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

FenF: servicing the Mycosubtilin synthetase assembly line in trans.

Authors :Aron ZD , Fortin PD , Calderone CT , Walsh CT

Published On :2007 Apr 16

Journal Article Research Support, N.I.H., Extramural

Crystallization and preliminary X-ray analysis of the O-methyltransferase NovP from the novobiocin-biosynthetic cluster of Streptomyces spheroides.

Authors :Stevenson CE , Freel Meyers CL , Walsh CT , Lawson DM

Published On :2007 Mar 1

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't