Publications | International Center for Genetic Disease at Harvard Medical School

Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands.

Authors :Mulichak AM , Lu W , Losey HC , Walsh CT , Garavito RM

Published On :2004 May 11

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.

Authors :Florez JC , Burtt N , de Bakker PI , Almgren P , Tuomi T , Holmkvist J , Gaudet D , Hudson TJ , Schaffner SF , Daly MJ , Hirschhorn JN , Groop L , Altshuler D

Published On :2004 May

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain.

Authors :Berry GT , Buccafusca R , Greer JJ , Eccleston E

Published On :2004 May

Journal Article Research Support, Non-U.S. Gov't

Proximodistal patterning of the limb: insights from evolutionary morphology.

Authors :Richardson MK , Jeffery JE , Tabin CJ

Published On :2004 Jan-Feb

Comparative Study Journal Article

Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors.

Authors :Jin Q , Anusaksathien O , Webb SA , Printz MA , Giannobile WV

Published On :2004 Apr

Journal Article Research Support, U.S. Gov't, P.H.S.

Effect of sustained gene delivery of platelet-derived growth factor or its antagonist (PDGF-1308) on tissue-engineered cementum.

Authors :Anusaksathien O , Jin Q , Zhao M , Somerman MJ , Giannobile WV

Published On :2004 Mar

Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Methods for high-density admixture mapping of disease genes.

Authors :Patterson N , Hattangadi N , Lane B , Lohmueller KE , Hafler DA , Oksenberg JR , Hauser SL , Smith MW , O'Brien SJ , Altshuler D , Daly MJ , Reich D

Published On :2004 May

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.

Authors :Lu W , Leimkuhler C , Oberthür M , Kahne D , Walsh CT

Published On :2004 Apr 20

Journal Article Research Support, U.S. Gov't, P.H.S.

Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin.

Authors :Lu W , Oberthür M , Leimkuhler C , Tao J , Kahne D , Walsh CT

Published On :2004 Mar 30

Journal Article Research Support, U.S. Gov't, P.H.S.

Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems.

Authors :Aach J , Church GM

Published On :2004 May 7

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.

Authors :Guilford WJ , Bauman JG , Skuballa W , Bauer S , Wei GP , Davey D , Schaefer C , Mallari C , Terkelsen J , Tseng JL , Shen J , Subramanyam B , Schottelius AJ , Parkinson JF

Published On :2004 Apr 8

Journal Article

Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations.

Authors :Rivier F , Alkan O , Flint AF , Muskiewicz K , Allen PD , Leboulch P , Gussoni E

Published On :2004 Apr 15

Journal Article Research Support, Non-U.S. Gov't

Digital quantitative measurements of gene expression.

Authors :Mikkilineni V , Mitra RD , Merritt J , DiTonno JR , Church GM , Ogunnaike B , Edwards JS

Published On :2004 Apr 20

Evaluation Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Uteroglobin: a potential novel tumor suppressor and molecular therapeutic for prostate cancer.

Authors :Patierno SR , Manyak MJ , Fernandez PM , Baker A , Weeraratna AT , Chou DS , Szlyk G , Geib KS , Walsh C , Patteras J

Published On :2002 Sep

Comparative Study Journal Article Research Support, Non-U.S. Gov't Review

Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion.

Authors :Kouprina N , Pavlicek A , Mochida GH , Solomon G , Gersch W , Yoon YH , Collura R , Ruvolo M , Barrett JC , Woods CG , Walsh CA , Jurka J , Larionov V

Published On :2004 May

Journal Article