Publications | International Center for Genetic Disease at Harvard Medical School

Protein-truncating mutations in ASPM cause variable reduction in brain size.

Authors :Bond J , Scott S , Hampshire DJ , Springell K , Corry P , Abramowicz MJ , Mochida GH , Hennekam RC , Maher ER , Fryns JP , Alswaid A , Jafri H , Rashid Y , Mubaidin A , Walsh CA , Roberts E , Woods CG

Published On :2003 Nov

Journal Article

Impact of selection, mutation rate and genetic drift on human genetic variation.

Authors :Sunyaev S , Kondrashov FA , Bork P , Ramensky V

Published On :2003 Dec 15

Journal Article

Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases: the C5 domain of tyrocidine synthetase is a (D)C(L) catalyst.

Authors :Clugston SL , Sieber SA , Marahiel MA , Walsh CT

Published On :2003 Oct 21

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Validation Study

Lung cancer in African Americans.

Authors :Higgins RS , Lewis C , Warren WH

Published On :2003 Oct

Comparative Study Journal Article

Understanding disparities in outcomes in cardiovascular medicine and thoracic oncology in African-American patients.

Authors :Higgins RS

Published On :2003 Oct

Journal Article

Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector.

Authors :Yamada K , Ramezani A , Hawley RG , Ebell W , Arwert F , Arnold LW , Walsh CE

Published On :2003 Oct

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Sugars, insulin sensitivity, and the postprandial state.

Authors :Daly M

Published On :2003 Oct

Journal Article Research Support, Non-U.S. Gov't Review

Platelet-derived growth factor gene delivery stimulates ex vivo gingival repair.

Authors :Anusaksathien O , Webb SA , Jin QM , Giannobile WV

Published On :2003 Aug

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Healing and osseointegration of submerged microtextured oral implants.

Authors :Oh TJ , Yoon J , Meraw SJ , Giannobile WV , Wang HL

Published On :2003 Oct

Journal Article Research Support, Non-U.S. Gov't

Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin.

Authors :Saunders AJ , Bertram L , Mullin K , Sampson AJ , Latifzai K , Basu S , Jones J , Kinney D , MacKenzie-Ingano L , Yu S , Albert MS , Moscarillo TJ , Go RC , Bassett SS , Daly MJ , Laird NM , Wang X , Velicelebi G , Wagner SL , Becker DK , Tanzi RE , Blacker D

Published On :2003 Nov 1

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells.

Authors :Nishioka K , Fujimori Y , Hashimoto-Tamaoki T , Kai S , Qiu H , Kobayashi N , Tanaka N , Westerman KA , Leboulch P , Hara H

Published On :2003 Oct

Journal Article Research Support, Non-U.S. Gov't

Loading peptidyl-coenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains.

Authors :Sieber SA , Walsh CT , Marahiel MA

Published On :2003 Sep 10

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Epimerization of an L-cysteinyl to a D-cysteinyl residue during thiazoline ring formation in siderophore chain elongation by pyochelin synthetase from Pseudomonas aeruginosa.

Authors :Patel HM , Tao J , Walsh CT

Published On :2003 Sep 9

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Biosynthesis of epothilone intermediates with alternate starter units: engineering polyketide-nonribosomal interfaces.

Authors :O'Connor SE , Walsh CT , Liu F

Published On :2003 Aug 25

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway.

Authors :Tao J , Hu S , Pacholec M , Walsh CT

Published On :2003 Sep 4

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.