Publications | International Center for Genetic Disease at Harvard Medical School

Predicting phenotype from patterns of annotation.

Authors :King OD , Lee JC , Dudley AM , Janse DM , Church GM , Roth FP

Published On :2003

Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Validation Study

Slice-selective J-coupled coherence transfer using symmetric linear phase pulses: applications to localized GABA spectroscopy.

Authors :Shen J

Published On :2003 Jul

Evaluation Study Journal Article

Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing.

Authors :Chao H , Mansfield SG , Bartel RC , Hiriyanna S , Mitchell LG , Garcia-Blanco MA , Walsh CE

Published On :2003 Aug

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Metabolites: a helping hand for pathway evolution?

Authors :Schmidt S , Sunyaev S , Bork P , Dandekar T

Published On :2003 Jun

Journal Article Review

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

Authors :Watanabe T , Shibata N , Westerman KA , Okitsu T , Allain JE , Sakaguchi M , Totsugawa T , Maruyama M , Matsumura T , Noguchi H , Yamamoto S , Hikida M , Ohmori A , Reth M , Weber A , Tanaka N , Leboulch P , Kobayashi N

Published On :2003 Jun 15

Journal Article Research Support, Non-U.S. Gov't

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

Authors :Mootha VK , Lindgren CM , Eriksson KF , Subramanian A , Sihag S , Lehar J , Puigserver P , Carlsson E , Ridderstråle M , Laurila E , Houstis N , Daly MJ , Patterson N , Mesirov JP , Golub TR , Tamayo P , Spiegelman B , Lander ES , Hirschhorn JN , Altshuler D , Groop LC

Published On :2003 Jul

Journal Article Research Support, Non-U.S. Gov't

Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression.

Authors :Kinoshita A , Wanibuchi H , Morimura K , Wei M , Shen J , Imaoka S , Funae Y , Fukushima S

Published On :2003 Aug

Journal Article Research Support, Non-U.S. Gov't

Chemoenzymatic route to macrocyclic hybrid peptide/polyketide-like molecules.

Authors :Kohli RM , Burke MD , Tao J , Walsh CT

Published On :2003 Jun 18

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

On the complete determination of biological systems.

Authors :Selinger DW , Wright MA , Church GM

Published On :2003 Jun

Comparative Study Journal Article

IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis.

Authors :Giallourakis C , Stoll M , Miller K , Hampe J , Lander ES , Daly MJ , Schreiber S , Rioux JD

Published On :2003 Jul

Journal Article

Gene therapy progress and prospects: gene therapy for the hemophilias.

Authors :Walsh CE

Published On :2003 Jun

Journal Article Review

Deconstructing phosphatases in limb development.

Authors :Dudley AT , Tabin CJ

Published On :2003 Jun

News Comment

Computational and experimental identification of C. elegans microRNAs.

Authors :Grad Y , Aach J , Hayes GD , Reinhart BJ , Church GM , Ruvkun G , Kim J

Published On :2003 May

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Lentivirus vector purification using anion exchange HPLC leads to improved gene transfer.

Authors :Yamada K , McCarty DM , Madden VJ , Walsh CE

Published On :2003 May

Evaluation Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Increased neuronal production, enlarged forebrains and cytoarchitectural distortions in beta-catenin overexpressing transgenic mice.

Authors :Chenn A , Walsh CA

Published On :2003 Jun

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.