Publications | International Center for Genetic Disease at Harvard Medical School

Oxidase domains in epothilone and bleomycin biosynthesis: thiazoline to thiazole oxidation during chain elongation.

Authors :Schneider TL , Shen B , Walsh CT

Published On :2003 Aug 19

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Single molecule profiling of alternative pre-mRNA splicing.

Authors :Zhu J , Shendure J , Mitra RD , Church GM

Published On :2003 Aug 8

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Fluorescent in situ sequencing on polymerase colonies.

Authors :Mitra RD , Shendure J , Olejnik J , Edyta-Krzymanska-Olejnik , Church GM

Published On :2003 Sep 1

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli.

Authors :Watanabe K , Rude MA , Walsh CT , Khosla C

Published On :2003 Aug 19

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Parallel competition analysis of Saccharomyces cerevisiae strains differing by a single base using polymerase colonies.

Authors :Merritt J , DiTonno JR , Mitra RD , Church GM , Edwards JS

Published On :2003 Aug 1

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming.

Authors :Walsh C , Freel Meyers CL , Losey HC

Published On :2003 Jul 31

Journal Article Review

Crystallization and preliminary X-ray studies on the putative dTDP sugar epimerase NovW from the novobiocin biosynthetic cluster of Streptomyces spheroides.

Authors :Jakimowicz P , Freel Meyers CL , Walsh CT , Buttner MJ , Lawson DM

Published On :2003 Aug

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway.

Authors :Mulichak AM , Losey HC , Lu W , Wawrzak Z , Walsh CT , Garavito RM

Published On :2003 Aug 5

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Wnt signaling during development of the gastrointestinal tract.

Authors :Theodosiou NA , Tabin CJ

Published On :2003 Jul 15

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Predicting phenotype from patterns of annotation.

Authors :King OD , Lee JC , Dudley AM , Janse DM , Church GM , Roth FP

Published On :2003

Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Validation Study

Slice-selective J-coupled coherence transfer using symmetric linear phase pulses: applications to localized GABA spectroscopy.

Authors :Shen J

Published On :2003 Jul

Evaluation Study Journal Article

Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing.

Authors :Chao H , Mansfield SG , Bartel RC , Hiriyanna S , Mitchell LG , Garcia-Blanco MA , Walsh CE

Published On :2003 Aug

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Metabolites: a helping hand for pathway evolution?

Authors :Schmidt S , Sunyaev S , Bork P , Dandekar T

Published On :2003 Jun

Journal Article Review

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

Authors :Watanabe T , Shibata N , Westerman KA , Okitsu T , Allain JE , Sakaguchi M , Totsugawa T , Maruyama M , Matsumura T , Noguchi H , Yamamoto S , Hikida M , Ohmori A , Reth M , Weber A , Tanaka N , Leboulch P , Kobayashi N

Published On :2003 Jun 15

Journal Article Research Support, Non-U.S. Gov't

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

Authors :Mootha VK , Lindgren CM , Eriksson KF , Subramanian A , Sihag S , Lehar J , Puigserver P , Carlsson E , Ridderstråle M , Laurila E , Houstis N , Daly MJ , Patterson N , Mesirov JP , Golub TR , Tamayo P , Spiegelman B , Lander ES , Hirschhorn JN , Altshuler D , Groop LC

Published On :2003 Jul

Journal Article Research Support, Non-U.S. Gov't