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Pediatric model-based dose optimization using a pooled exposure-response safety analysis for nivolumab and nivolumab plus ipilimumab combination in melanoma.

Authors :Du S , Zhao Y , Hu Z , Liu S , Roy A , Shen J , Zhu L , Hamuro L
Published On :2024 Jan
Journal Article


Exome copy number variant detection, analysis and classification in a large cohort of families with undiagnosed rare genetic disease.

Authors :Lemire G , Sanchis-Juan A , Russell K , Baxter S , Chao KR , Singer-Berk M , Groopman E , Wong I , England E , Goodrich J , Pais L , Austin-Tse C , DiTroia S , O'Heir E , Ganesh VS , Wojcik MH , Evangelista E , Snow H , Osei-Owusu I , Fu J , Singh M , Mostovoy Y , Huang S , Garimella K , Kirkham SL , Neil JE , Shao DD , Walsh CA , Argili E , Le C , Sherr EH , Gleeson J , Shril S , Schneider R , Hildebrandt F , Sankaran VG , Madden JA , Genetti CA , Beggs AH , Agrawal PB , Bujakowska KM , Place E , Pierce EA , Donkervoort S , Bönnemann CG , Gallacher L , Stark Z , Tan T , White SM , Töpf A , Straub V , Fleming MD , Pollak MR , Õunap K , Pajusalu S , Donald KA , Bruwer Z , Ravenscroft G , Laing NG , MacArthur DG , Rehm HL , Talkowski ME , Brand H , O'Donnell-Luria A
Published On :2023 Oct 5
Journal Article


Meningococcal disease in the Middle East: A report from the Global Meningococcal Initiative.

Authors :Al-Abri SS , Abuhasan MY , Albayat SSA , Bai X , Bastaki H , Borrow R , Caugant DA , Dbaibo G , Deghmane AE , Dinleyici EC , Ghuneim N , Sheek-Hussein M , Lucidarme J , Leng S , Koliou MG , Sáfadi MAP , Salman JA , Al-Sanouri T , Smith V , Taha MK , Vázquez J , Wright C , Yezli S
Published On :2024 Feb
Journal Article Review


Doppler ultrasonographic evaluation of tissue revascularization following connective tissue graft at implant sites.

Authors :Tavelli L , Kripfgans OD , Chan HL , Vera Rodriguez M , Sabri H , Mancini L , Wang HL , Giannobile WV , Barootchi S
Published On :2025 Jan
Journal Article Randomized Controlled Trial


Engineering Ca(2+)-Dependent DNA Polymerase Activity.

Authors :Biggs BW , de Paz AM , Bhan NJ , Cybulski TR , Church GM , Tyo KEJ
Published On :2023 Nov 17
Journal Article


Selective BET inhibitor RVX-208 ameliorates periodontal inflammation and bone loss.

Authors :Sun M , Clayton N , Alam S , Asmussen N , Wong A , Kim JH , Luong G , Mokhtari S , Pellei D , Carrico CK , Schwartz Z , Boyan BD , Giannobile WV , Sahingur SE , Lin Z
Published On :2023 Dec
Journal Article


Profiling the inflammatory bowel diseases using genetics, serum biomarkers, and smoking information.

Authors :Liu R , Li D , Haritunians T , Ruan Y , Daly MJ , Huang H , McGovern DPB
Published On :2023 Oct 20
Journal Article


CD24hiCD27+ Bregs within Metastatic Lymph Nodes Promote Multidrug Resistance in Breast Cancer.

Authors :Huang H , Yao Y , Shen L , Jiang J , Zhang T , Xiong J , Li J , Sun S , Zheng S , Jia F , Zhou J , Yu X , Chen W , Shen J , Xia W , Shao X , Wang Q , Huang J , Ni C
Published On :2023 Dec 15
Journal Article


SeqVerify: An accessible analysis tool for cell line genomic integrity, contamination, and gene editing outcomes.

Authors :Smela MP , Pepe V , Church GM
Published On :2023 Oct 28
Journal Article


Epilepsy in cardiofaciocutaneous syndrome: Clinical burden and response to anti-seizure medication.

Authors :Kenney-Jung DL , Collazo-Lopez JE , Rogers DJ , Shanley R , Zatkalik AL , Whitmarsh AE , Roberts AE , Zenker M , Pierpont EI
Published On :2024 Feb
Journal Article


Comparative transcriptomics reveals human-specific cortical features.

Authors :Jorstad NL , Song JHT , Exposito-Alonso D , Suresh H , Castro-Pacheco N , Krienen FM , Yanny AM , Close J , Gelfand E , Long B , Seeman SC , Travaglini KJ , Basu S , Beaudin M , Bertagnolli D , Crow M , Ding SL , Eggermont J , Glandon A , Goldy J , Kiick K , Kroes T , McMillen D , Pham T , Rimorin C , Siletti K , Somasundaram S , Tieu M , Torkelson A , Feng G , Hopkins WD , Höllt T , Keene CD , Linnarsson S , McCarroll SA , Lelieveldt BP , Sherwood CC , Smith K , Walsh CA , Dobin A , Gillis J , Lein ES , Hodge RD , Bakken TE
Published On :2023 Oct 13
Journal Article


Design and testing of a humanized porcine donor for xenotransplantation.

Authors :Anand RP , Layer JV , Heja D , Hirose T , Lassiter G , Firl DJ , Paragas VB , Akkad A , Chhangawala S , Colvin RB , Ernst RJ , Esch N , Getchell K , Griffin AK , Guo X , Hall KC , Hamilton P , Kalekar LA , Kan Y , Karadagi A , Li F , Low SC , Matheson R , Nehring C , Otsuka R , Pandelakis M , Policastro RA , Pols R , Queiroz L , Rosales IA , Serkin WT , Stiede K , Tomosugi T , Xue Y , Zentner GE , Angeles-Albores D , Chris Chao J , Crabtree JN , Harken S , Hinkle N , Lemos T , Li M , Pantano L , Stevens D , Subedar OD , Tan X , Yin S , Anwar IJ , Aufhauser D , Capuano S , Kaufman DB , Knechtle SJ , Kwun J , Shanmuganayagam D , Markmann JF , Church GM , Curtis M , Kawai T , Youd ME , Qin W
Published On :2023 Oct
Journal Article


Biological differences between normal and cancer-associated fibroblasts in breast cancer.

Authors :Hu D , Zhuo W , Gong P , Ji F , Zhang X , Chen Y , Mao M , Ju S , Pan Y , Shen J
Published On :2023 Sep
Journal Article


Heterozygous loss-of-function SMC3 variants are associated with variable and incompletely penetrant growth and developmental features.

Authors :Ansari M , Faour KNW , Shimamura A , Grimes G , Kao EM , Denhoff ER , Blatnik A , Ben-Isvy D , Wang L , Helm BM , Firth H , Breman AM , Bijlsma EK , Iwata-Otsubo A , de Ravel TJL , Fusaro V , Fryer A , Nykamp K , Stühn LG , Haack TB , Korenke GC , Constantinou P , Bujakowska KM , Low KJ , Place E , Humberson J , Napier MP , Hoffman J , Juusola J , Deardorff MA , Shao W , Rockowitz S , Krantz I , Kaur M , Raible S , Kliesch S , Singer-Berk M , Groopman E , DiTroia S , Ballal S , Srivastava S , Rothfelder K , Biskup S , Rzasa J , Kerkhof J , McConkey H , O'Donnell-Luria A , Sadikovic B , Hilton S , Banka S , Tüttelmann F , Conrad D , Talkowski ME , FitzPatrick DR , Boone PM
Published On :2023 Sep 28
Journal Article


Multiple TP53 p.R337H haplotypes and implications for tumor susceptibility.

Authors :Pinto EM , Fridman C , Figueiredo BC , Salvador H , Teixeira MR , Pinto C , Pinheiro M , Kratz CP , Lavarino C , Legal EAMF , Le A , Kelly G , Koeppe E , Stoffel EM , Breen K , Hahner S , Heinze B , Techavichit P , Krause A , Ogata T , Fujisawa Y , Walsh MF , Rana HQ , Maxwell KN , Garber JE , Rodriguez-Galindo C , Ribeiro RC , Zambetti GP
Published On :2024 Jan 11
Journal Article