Publications | International Center for Genetic Disease at Harvard Medical School

Prognostic impact of HER2-low expression in HER2-negative breast cancer under different hormone receptor status.

Authors :Xu B , Shen J , Shen J , Wang L

Published On :2023 Apr

Journal Article

Federated learning with hyper-network-a case study on whole slide image analysis.

Authors :Lin Y , Wang H , Li W , Shen J

Published On :2023 Jan 31

Journal Article

Beyond the exome: what's next in diagnostic testing for Mendelian conditions.

Authors :Wojcik MH , Reuter CM , Marwaha S , Mahmoud M , Duyzend MH , Barseghyan H , Yuan B , Boone PM , Groopman EE , Délot EC , Jain D , Sanchis-Juan A , Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium , Starita LM , Talkowski M , Montgomery SB , Bamshad MJ , Chong JX , Wheeler MT , Berger SI , O'Donnell-Luria A , Sedlazeck FJ , Miller DE

Published On :2023 Jan 18

Journal Article

Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.

Authors :Ganz J , Luquette LJ , Bizzotto S , Bohrson CL , Jin H , Miller MB , Zhou Z , Galor A , Park PJ , Walsh CA

Published On :2023 Jan 14

Journal Article

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases.

Authors :Yuan K , Longchamps RJ , Pardiñas AF , Yu M , Chen TT , Lin SC , Chen Y , Lam M , Liu R , Xia Y , Guo Z , Shi W , Shen C , Schizophrenia Workgroup of Psychiatric Genomics Consortium , Daly MJ , Neale BM , Feng YA , Lin YF , Chen CY , O'Donovan M , Ge T , Huang H

Published On :2023 Jul 9

Journal Article

Selenite reduced uptake/translocation of cadmium via regulation of assembles and interactions of pectins, hemicelluloses, lignins, callose and Casparian strips in rice roots.

Authors :Wang L , Wu K , Liu Z , Li Z , Shen J , Wu Z , Liu H , You L , Yang G , Rensing C , Feng R

Published On :2023 Apr 15

Journal Article

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Authors :Demontis D , Walters GB , Athanasiadis G , Walters R , Therrien K , Nielsen TT , Farajzadeh L , Voloudakis G , Bendl J , Zeng B , Zhang W , Grove J , Als TD , Duan J , Satterstrom FK , Bybjerg-Grauholm J , Bækved-Hansen M , Gudmundsson OO , Magnusson SH , Baldursson G , Davidsdottir K , Haraldsdottir GS , Agerbo E , Hoffman GE , Dalsgaard S , Martin J , Ribasés M , Boomsma DI , Soler Artigas M , Roth Mota N , Howrigan D , Medland SE , Zayats T , Rajagopal VM , ADHD Working Group of the Psychiatric Genomics Consortium , iPSYCH-Broad Consortium , Nordentoft M , Mors O , Hougaard DM , Mortensen PB , Daly MJ , Faraone SV , Stefansson H , Roussos P , Franke B , Werge T , Neale BM , Stefansson K , Børglum AD

Published On :2023 Feb

Meta-Analysis Journal Article

The role of 25(OH)D3 and circRNAs in early diagnosis of gestational diabetes mellitus.

Authors :Zou J , Liu Y , Shen J , Xue A , Yan L , Zhang Y

Published On :2023 Feb

Journal Article

Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease.

Authors :Morton SU , Norris-Brilliant A , Cunningham S , King E , Goldmuntz E , Brueckner M , Miller TA , Thomas NH , Liu C , Adams HR , Bellinger DC , Cleveland J , Cnota JF , Dale AM , Frommelt M , Gelb BD , Grant PE , Goldberg CS , Huang H , Kuperman JM , Li JS , McQuillen PS , Panigrahy A , Porter GA Jr , Roberts AE , Russell MW , Seidman CE , Tivarus ME , Anagnoustou E , Hagler DJ Jr , Chung WK , Newburger JW

Published On :2023 Jan 3

Journal Article

COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation.

Authors :Patton MJ , Orihuela CJ , Harrod KS , Bhuiyan MAN , Dominic P , Kevil CG , Fort D , Liu VX , Farhat M , Koff JL , Lal CV , Gaggar A , Richter RP , Erdmann N , Might M , Gaggar A

Published On :2023 Jan 23

Multicenter Study Journal Article

Overcoming roadblocks in clinical innovation via high fidelity simulation: use of a phantom simulator to achieve FDA and IRB approval of a clinical trial of fetal embolization of vein of Galen malformations.

Authors :Orbach DB , Wilkins-Haug LE , Benson CB , Rangwala SD , Pak C , Saffarzadeh M , Weinstock P

Published On :2023 Dec

Journal Article

Open-source lower controller for twelve degrees of freedom hydraulic quadruped robot with distributed control scheme.

Authors :Fang L , Zhang J , Zong H , Wang X , Zhang K , Shen J , Lu Z

Published On :2023 Mar

Journal Article

Neurochemical correlations in short echo time proton magnetic resonance spectroscopy.

Authors :Hong S , Shen J

Published On :2023 Jul

Journal Article

A Super Anticorrosive Ultrathin Film by Restarting the Native Passive Film on 316L Stainless Steel.

Authors :Ren Y , Li Y , Kang Z , Zhang X , Wu S , Shen J , Zhou G

Published On :2023 Jan 16

Journal Article

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system.

Authors :Akula SK , Marciano JH , Lim Y , Exposito-Alonso D , Hylton NK , Hwang GH , Neil JE , Dominado N , Bunton-Stasyshyn RK , Song JHT , Talukdar M , Schmid A , Teboul L , Mo A , Shin T , Finander B , Beck SG , Yeh RC , Otani A , Qian X , DeGennaro EM , Alkuraya FS , Maddirevula S , Cascino GD , Giannini C , Undiagnosed Diseases Network , Burrage LC , Rosenfield JA , Ketkar S , Clark GD , Bacino C , Lewis RA , Segal RA , Bazan JF , Smith KA , Golden JA , Cho G , Walsh CA

Published On :2023 Jan 24

Journal Article