Publications | International Center for Genetic Disease at Harvard Medical School

Reconstructing Earth's atmospheric oxygenation history using machine learning.

Authors :Chen G , Cheng Q , Lyons TW , Shen J , Agterberg F , Huang N , Zhao M

Published On :2022 Oct 4

Journal Article

Single-sequence protein structure prediction using a language model and deep learning.

Authors :Chowdhury R , Bouatta N , Biswas S , Floristean C , Kharkar A , Roy K , Rochereau C , Ahdritz G , Zhang J , Church GM , Sorger PK , AlQuraishi M

Published On :2022 Nov

Journal Article

The Genetics of Neurodevelopment in Congenital Heart Disease.

Authors :Patt E , Singhania A , Roberts AE , Morton SU

Published On :2023 Feb

Journal Article Review

Comparative analysis of very volatile organic compounds and odors released from decorative medium density fiberboard using gas chromatography-mass spectrometry and olfactory detection.

Authors :Wang W , Shen J , Liu M , Xu W , Wang H , Chen Y

Published On :2022 Dec

Journal Article

Developmental dynamics of RNA translation in the human brain.

Authors :Duffy EE , Finander B , Choi G , Carter AC , Pritisanac I , Alam A , Luria V , Karger A , Phu W , Sherman MA , Assad EG , Pajarillo N , Khitun A , Crouch EE , Ganesh S , Chen J , Berger B , Sestan N , O'Donnell-Luria A , Huang EJ , Griffith EC , Forman-Kay JD , Moses AM , Kalish BT , Greenberg ME

Published On :2022 Oct

Journal Article

Clinical and patient-reported outcomes of tissue engineering strategies for periodontal and peri-implant reconstruction.

Authors :Tavelli L , Barootchi S , Rasperini G , Giannobile WV

Published On :2023 Feb

Journal Article Review

Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.

Authors :Luquette LJ , Miller MB , Zhou Z , Bohrson CL , Zhao Y , Jin H , Gulhan D , Ganz J , Bizzotto S , Kirkham S , Hochepied T , Libert C , Galor A , Kim J , Lodato MA , Garaycoechea JI , Gawad C , West J , Walsh CA , Park PJ

Published On :2022 Oct

Journal Article

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.

Authors :Mattheisen M , Grove J , Als TD , Martin J , Voloudakis G , Meier S , Demontis D , Bendl J , Walters R , Carey CE , Rosengren A , Strom NI , Hauberg ME , Zeng B , Hoffman G , Zhang W , Bybjerg-Grauholm J , Bækvad-Hansen M , Agerbo E , Cormand B , Nordentoft M , Werge T , Mors O , Hougaard DM , Buxbaum JD , Faraone SV , Franke B , Dalsgaard S , Mortensen PB , Robinson EB , Roussos P , Neale BM , Daly MJ , Børglum AD

Published On :2022 Oct

Journal Article

Evolution of the ancestral mammalian karyotype and syntenic regions.

Authors :Damas J , Corbo M , Kim J , Turner-Maier J , Farré M , Larkin DM , Ryder OA , Steiner C , Houck ML , Hall S , Shiue L , Thomas S , Swale T , Daly M , Korlach J , Uliano-Silva M , Mazzoni CJ , Birren BW , Genereux DP , Johnson J , Lindblad-Toh K , Karlsson EK , Nweeia MT , Johnson RN , Zoonomia Consortium , Lewin HA

Published On :2022 Oct 4

Journal Article

Lovo-cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB-206 study.

Authors :Kanter J , Thompson AA , Pierciey FJ Jr , Hsieh M , Uchida N , Leboulch P , Schmidt M , Bonner M , Guo R , Miller A , Ribeil JA , Davidson D , Asmal M , Walters MC , Tisdale JF

Published On :2023 Jan

Journal Article

Upregulating HIF-1α to Boost the Survival of Neural Stem Cells via Functional Peptides-Complexed MRI-Visible Nanomedicine for Stroke Therapy.

Authors :Wang Z , Cai Y , Zhang Q , Li J , Lin B , Zhao J , Zhang F , Li Y , Yang X , Lu L , Shuai X , Shen J

Published On :2022 Dec

Journal Article

Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery Disease.

Authors :Maamari DJ , Brockman DG , Aragam K , Pelletier RC , Folkerts E , Neben CL , Okumura S , Hull LE , Philippakis AA , Natarajan P , Ellinor PT , Ng K , Zhou AY , Khera AV , Fahed AC

Published On :2022 Aug

Journal Article

Successful Derivation of Hepatoblasts, Cholangiocytes and Hepatocytes from Simian Induced Pluripotent Stem Cells.

Authors :Luce E , Steichen C , Abed S , Weber A , Leboulch P , Maouche-Chrétien L , Dubart-Kupperschmitt A

Published On :2022 Sep 17

Journal Article

SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests.

Authors :Zhou W , Bi W , Zhao Z , Dey KK , Jagadeesh KA , Karczewski KJ , Daly MJ , Neale BM , Lee S

Published On :2022 Oct

Journal Article

Differences in Cancer Phenotypes Among Frequent CHEK2 Variants and Implications for Clinical Care-Checking CHEK2.

Authors :Bychkovsky BL , Agaoglu NB , Horton C , Zhou J , Yussuf A , Hemyari P , Richardson ME , Young C , LaDuca H , McGuinness DL , Scheib R , Garber JE , Rana HQ

Published On :2022 Nov 1

Journal Article