Publications | International Center for Genetic Disease at Harvard Medical School

Recurrent mutation in the ancestry of a rare variant.

Authors :Wakeley J , Fan WL , Koch E , Sunyaev S

Published On :2023 Jul 6

Journal Article

Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.

Authors :Dec E , Clement J , Cheng K , Church GM , Fossel MB , Rehkopf DH , Rosero-Bixby L , Kobor MS , Lin DT , Lu AT , Fei Z , Guo W , Chew YC , Yang X , Putra SED , Reiner AP , Correa A , Vilalta A , Pirazzini C , Passarino G , Monti D , Arosio B , Garagnani P , Franceschi C , Horvath S

Published On :2023 Jun

Journal Article

Why 2 dental degrees?: Time for unification of degrees and oral health care providers.

Authors :Giddon DB , Giannobile WV

Published On :2023 Aug

Editorial Comment

A systematic review of adeno-associated virus gene therapy clinical trials for HIV - A potential solution for patients with haemophilia and HIV?

Authors :Levy-Mendelovich S , Walsh CE , Schapiro JM , Soffer S , Klang E , Kenet G

Published On :2023 May

Journal Article

Correction: Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression.

Authors :Pierson Smela MD , Kramme CC , Fortuna PRJ , Adams JL , Su AR , Dong E , Kobayashi M , Brixi G , Kavirayuni VS , Tysinger E , Kohman RE , Shioda T , Chatterjee P , Church GM

Published On :2023 Mar 22

Published Erratum

Advanced variant classification framework reduces the false positive rate of predicted loss of function (pLoF) variants in population sequencing data.

Authors :Singer-Berk M , Gudmundsson S , Baxter S , Seaby EG , England E , Wood JC , Son RG , Watts NA , Karczewski KJ , Harrison SM , MacArthur DG , Rehm HL , O'Donnell-Luria A

Published On :2023 Mar 9

Journal Article

PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.

Authors :Koseki S , Hong L , Yudistyra V , Stan T , Tysinger E , Silverstein R , Kramme C , Amrani N , Savic N , Pacesa M , Rodriguez T , Ponnapati M , Jacobson J , Church G , Truant R , Jinek M , Kleinstiver B , Sontheimer E , Chatterjee P

Published On :2023 Mar 7

Journal Article

Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.

Authors :Khurshid S , Lazarte J , Pirruccello JP , Weng LC , Choi SH , Hall AW , Wang X , Friedman SF , Nauffal V , Biddinger KJ , Aragam KG , Batra P , Ho JE , Philippakis AA , Ellinor PT , Lubitz SA

Published On :2023 Mar 21

Journal Article

Classification and Prediction of Skyrmion Material Based on Machine Learning.

Authors :Liu D , Liu Z , Zhang J , Yin Y , Xi J , Wang L , Xiong J , Zhang M , Zhao T , Jin J , Hu F , Sun J , Shen J , Shen B

Published On :2023

Journal Article

Coronally advanced flap versus tunnel technique for the treatment of peri-implant soft tissue dehiscences with the connective tissue graft: A randomized, controlled clinical trial.

Authors :Tavelli L , Majzoub J , Kauffmann F , Rodriguez MV , Mancini L , Chan HL , Kripfgans OD , Giannobile WV , Wang HL , Barootchi S

Published On :2023 Jul

Randomized Controlled Trial Journal Article

GWAS meta-analyses clarify the genetics of cervical phenotypes and inform risk stratification for cervical cancer.

Authors :Koel M , Võsa U , Jõeloo M , Läll K , Gualdo NP , Laivuori H , Lemmelä S , Estonian Biobank Research Team; FinnGen , Daly M , Palta P , Mägi R , Laisk T

Published On :2023 Jun 5

Journal Article

Infliximab response associates with radiologic findings in bio-naïve Crohn's disease.

Authors :Yueying C , Jing F , Qi F , Jun S

Published On :2023 Aug

Multicenter Study Journal Article

The aging of glymphatic system in human brain and its correlation with brain charts and neuropsychological functioning.

Authors :Dai Z , Yang Z , Chen X , Zheng W , Zhuang Z , Liao Y , Li M , Chen S , Lin D , Wu X , Shen J

Published On :2023 Jun 8

Journal Article

A swapped genetic code prevents viral infections and gene transfer.

Authors :Nyerges A , Vinke S , Flynn R , Owen SV , Rand EA , Budnik B , Keen E , Narasimhan K , Marchand JA , Baas-Thomas M , Liu M , Chen K , Chiappino-Pepe A , Hu F , Baym M , Church GM

Published On :2023 Mar

Journal Article

The value of quantitative plaque analysis based on coronary computed tomography angiography in predicting the percutaneous coronary intervention outcome of chronic total occlusion lesions.

Authors :Du G , Cao M , Hou Z , Cai Z , Yu T , Zheng H , Dai Z , Yang Z , Shen J , Lin D

Published On :2023 Mar 1

Journal Article