Publications | International Center for Genetic Disease at Harvard Medical School

Loss of CFHR5 function reduces the risk for age-related macular degeneration.

Authors :Reeve MP , Loomis S , Nissilä E , Soare TW , Rausch T , Zheng Z , Della Briotta Parolo P , Ben-Isvy D , Aho E , Cesetti E , Okunuki Y , McLaughlin H , Mäkelä J , FinnGen , Kurki M , Talkowski ME , Korbel JO , Connor K , Meri S , Daly MJ , Runz H

Published On :2025 Jul 1

Journal Article

Infantile Developmental Regression, Asymptomatic Abnormal Newborn Screen, and a Shared Diagnosis.

Authors :Joy Wang M , Lueck T , Gilmartin A , Sacharow S , Gupta M

Published On :2025 Jul 1

Journal Article

A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections.

Authors :Wang C , Shen J , Muhetaer M , Zhang S , Sun J , He Z , Wang Y , Luo C

Published On :2025

Journal Article

Hotspots of human mutation point to clonal expansions in spermatogonia.

Authors :Seplyarskiy V , Moldovan MA , Koch E , Kar P , Neville MD , Rahbari R , Sunyaev S

Published On :2025 Aug 15

Journal Article

Iron modulated high entropy engineering boosting alkaline oxygen evolution.

Authors :Qin J , Tang M , Zhang H , Tian J , Shen J

Published On :2025 Dec

Journal Article

Author Correction: Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design.

Authors :German J , Yang Z , Urbut S , Vartiainen P , FinnGen , Natarajan P , Patorno E , Kutalik Z , Philippakis A , Ganna A

Published On :2025 Aug

Published Erratum

Healthy euploid dizygotic twin birth after transfer of nonmosaic aneuploid embryos.

Authors :Tise CG , Verma K , Rivera-Cruz G , Chamanara S , Gerber SK , Boyd A , Mazzoni R , Nel-Themaat L , Behr B , Milki AA , Lathi RB

Published On :2025 Jun 25

Journal Article

Accuracy and Efficiency of Artificial Intelligence and Manual Virtual Segmentation for Generation of 3D Printed Tooth Replicas.

Authors :Pedrinaci I , Nasseri A , Calatrava J , Couso-Queiruga E , Giannobile WV , Gallucci GO , Sanz M

Published On :2025 Jun 25

Journal Article

Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish.

Authors :Wolford BN , Zhao QY , Wu KH , Yu X , Richter CE , Bhatta L , Brumpton BM , Desch KC , Thibord F , Klarin D , Johnson AD , Trégouët DA , Damrauer SM , Smith NL , Lo Faro V , Tsuo K , Daly MJ , Neale BM , Zhou W , Willer CJ , Shavit JA , Surakka I

Published On :2025 Oct 14

Journal Article

Sandwich-Layered Structure Nanofiber Conduits Facilitating the Repair of Long-Gap Nerve Defects.

Authors :Ye L , Chen P , Liu Y , Shen J , Saijilafu , Zhang P , Liu Y , Xu R

Published On :2025 Jun 17

Journal Article

Brachyury-Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment.

Authors :Gong Y , Shi W , Liu X , Yu H , Wu Y , Xia Y , Yue C , Yang C , Shen C , Pei R , Xin T , Pei H , Shen J

Published On :2025 Sep

Journal Article

Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients.

Authors :Yang L , Wang K , Liu B , Chen T , Ma T , Cui Z , Zhang D , Zhang S , Liu X , Shen J , Lu H

Published On :2025

Journal Article

Practice-based Research and Education for Dental Pain: Coupling Risk Stratification and Artificial Intelligence for Clinical Translation.

Authors :Giannobile WV , Park SE , Barrow JR , Hayes C , Yoshida M , Kim AS , Yilmaz BT , Nadler LM , Gibbs JL

Published On :2025 Jun 18

Journal Article

Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design.

Authors :German J , Yang Z , Urbut S , Vartiainen P , FinnGen , Natarajan P , Patorno E , Kutalik Z , Philippakis A , Ganna A

Published On :2025 Jul

Journal Article

Skin health and biological aging.

Authors :Furman D , Auwerx J , Bulteau AL , Church G , Couturaud V , Crabbe L , Davies KJA , Decottignies A , Gladyshev VN , Kennedy BK , Neretti N , Nizard C , Pays K , Robinton D , Sebastiano V , Watson REB , Wang MC , Woltjen K

Published On :2025 Jul

Journal Article Review