Publications | International Center for Genetic Disease at Harvard Medical School

Milk fat globule membrane supplementation in formula modulates the gut microbiome and metabolic status of piglets and normalizes intestinal development.

Authors :Zhou Z , Liu B , Shen J , Yan C , Yang G , Zhang Y , Zhao J , Chen L

Published On :2025

Journal Article

Unlocking the potential of FinnGen to advance cancer research.

Authors :Aavikko M , Liu A , Daly M

Published On :2026 Mar

Journal Article

Segmentation of glioma sub-regions based on EnnUnet in tumor treating fields.

Authors :Wang L , Chen C , Xiao Y , Gong R , Shen J , Lu M

Published On :2025 Oct 27

Journal Article

Frequency and clinical features of germline pathogenic variants in sarcoma: a case-control study.

Authors :Rodriguez-Hernandez A , Horiguchi M , Horton C , Polfus LM , Bychkovsky BL , Buehler RM , George S , Merriam P , Garber JE , Rana HQ

Published On :2026 Jan 1

Journal Article

SMARCA4 pathogenic variants: Gynecological cancer histories from a laboratory tested cohort.

Authors :Borden BA , Rodriguez-Hernandez A , Trottier M , Horiguchi M , Weyandt JD , Horton C , Polfus LM , Bychkovsky BL , Young CC , Garber JE , St Laurent JD , Rana HQ

Published On :2025 Nov

Journal Article

Gastroenterologists' attitudes and challenges toward treat-to-target strategies in inflammatory bowel disease: a multinational survey.

Authors :You Z , Shen J , Ahuja V , Watermeyer G , Steinwurz F , Shapina M , Fiocchi C , Ran Z

Published On :2025

Journal Article

Corrigendum to "The burden of early onset psychosis: Diagnostic complexity, high comorbidity, and poor functioning in patients and their relatives" [Schizophr. Res. Volume 285, November 2025, Pages 165-174].

Authors :Mollon J , Lanzagorta N , Mathias SR , Rodrigue A , Knowles EEM , Deaso E , Cadavid L , Saavedra JU , Brownstein C , D'Angelo E , Gonzalez-Heydrich J , Ramírez PZ , Sarmiento E , Bustamante C , Walsh CA , Almasy L , Nicolini H , Glahn DC

Published On :2025 Nov

Published Erratum

Hotspots of human mutation point to clonal expansions in spermatogonia.

Authors :Seplyarskiy V , Moldovan MA , Koch E , Kar P , Neville MDC , Rahbari R , Sunyaev S

Published On :2025 Nov

Journal Article

Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae.

Authors :Smidler AL , Marrogi EA , Scott S , Mameli E , Abernathy D , Akbari OS , Church GM , Catteruccia F , Esvelt K

Published On :2025 Oct 8

Journal Article

Tuberculosis Disease Prevalence Among People Who Smoke Illicit Drugs: A Respondent- Driven Sampling Study in the Western Cape, South Africa.

Authors :Malatesta S , Carney T , Niemand Wolhuter N , Overbeck V , Theron D , Weber SE , Meade CS , Thomson S , Bouton TC , Farhat M , Myers B , Wood R , Ratangee F , Horsburgh CR , White LF , Warren RM , Jacobson KR

Published On :2025 Oct 8

Journal Article

Artificial intelligence model for automatic 3-dimensional reconstruction of ossicular chain and bony labyrinth from high-resolution CT.

Authors :Xie M , Wang H , Yang Z , Gao M , Shi G , Liao X , Luo Z , Li X , Shen J

Published On :2025 Jan

Journal Article

Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians.

Authors :Raj APMS , Selvakumar G , Clement J , Church GM , Sivasubramaniam S

Published On :2025 Oct 7

Journal Article

Improved allele frequencies in gnomAD through local ancestry inference.

Authors :Kore P , Wilson MW , Tiao G , Chao K , Darnowsky PW , Watts NA , Mauer JH , Baxter SM , Genome Aggregation Database Consortium , Rehm HL , Daly MJ , Karczewski KJ , Atkinson EG

Published On :2025 Oct 6

Journal Article

Enhancing randomized clinical trials with digital twins.

Authors :Akbarialiabad H , Pasdar A , Murrell DF , Mostafavi M , Shakil F , Safaee E , Leachman SA , Haghighi A , Tarbox M , Bunick CG , Grada A

Published On :2025 Oct 3

Journal Article Review

Etrasimod as induction and maintenance treatment for patients with moderately to severely active ulcerative colitis in East Asia (ENLIGHT UC): a randomised, double-blind, placebo-controlled, multicentre, phase 3 study.

Authors :Wu K , Zheng C , Cao Q , Ding Y , Gao X , Zhong J , Chiu CT , Zhang H , Wang X , Wang B , Liang J , Liu X , Zhou Y , Xu B , Kim TO , Shen X , Chen D , Chen W , Liu Y , Shen J , Liu F , Ding X , Zhan Q , Chou JW , Zeng S , Lin Y , Ying L , Chen X , ENLIGHT UC Study Group

Published On :2025 Dec

Journal Article Randomized Controlled Trial Multicenter Study Clinical Trial, Phase III