Publications | International Center for Genetic Disease at Harvard Medical School

Developing Predictive Models for Periodontitis Progression Using Artificial Intelligence: A Longitudinal Cohort Study.

Authors :Furquim CP , Caruth L , Chandrasekaran G , Cucchiara A , Kallan MJ , Martin L , Feres M , Bittinger K , Divaris K , Glessner J , Kantarci A , Giannobile W , Verma SS , Teles F

Published On :2025 Oct

Journal Article Multicenter Study

Comments on "Genetic and clinical characteristics of catecholaminergic polymorphic ventricular tachycardia in a Taiwanese nationwide cohort".

Authors :Shen B , Shen J

Published On :2025 Aug 18

Letter

Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1.

Authors :Oh HS , Chou S-F , Raja P , Shim J , Das B , Pesola JM , Romero N , Lee JS , Ng A , Buttermore ED , Church G , Woolf CJ , Coen DM , Knipe DM

Published On :2025 Sep 10

Journal Article

Efficacy of minimally invasive small-incision-assisted reduction with percutaneous Kirschner wire fixation in pediatric supracondylar humerus fractures.

Authors :Mao Y , Zhang A , Shen J , Tang K , Wang L

Published On :2025

Journal Article

Exposure-Response Analysis of Repotrectinib to Support the Dose Recommendation for Patients With ROS1-Positive NSCLC or NTRK-Positive Solid Tumors.

Authors :Du S , Hu Z , Shen J , Zhu L , Roy A , Lam J , Lu M , Kondic A , Hamuro L

Published On :2025 Dec

Journal Article

Kun-Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile.

Authors :Shen Y , Liu T , Liu J , Han X , Wu J , Xie L , Chen X , Xu B , Sun Y , Xu S , Zhang Q , Xie N , Zhang L , Ji J , Mo W , Liu Y , Shi X , Shen J , Qiu W , Huang J , Shen Q , Zhai Y , Xu H , KQBC group

Published On :2025 Aug 16

Journal Article

Initiation of meiosis from human iPSCs under defined conditions through identification of regulatory factors.

Authors :Smela MP , Adams J , Ma C , Breimann L , Widocki U , Dobre B , Shioda T , Church GM

Published On :2025 Aug 15

Journal Article

Simulating a for-loop in the human genome: Design and evaluation of recombinase genetic programs that count to three.

Authors :Chao G , Appleton E , Gutierrez CS , Evgeniou L , Daifuku T , Wannier T , Mintzer E , Church GM

Published On :2025 Aug 5

Journal Article Preprint

Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.

Authors :Bhérer C , Grenier JC , Pelletier J , Boucher G , Gagnon G , Goyette P , Ashton-Beaucage D , Stevens C , Battat R , Bitton A , Campeau PM , Laprise C , NIDDK IBD Genetics Consortium , Quebec IBD Genetics Consortium , iGenoMed Consortium , Huang H , Daly M , Taliun D , Hussin JG , Mooser V , Rioux JD

Published On :2025 Jul 14

Journal Article Preprint

A simple, ultrastable, and cost-effective oxygen-scavenging system for long-term DNA-PAINT imaging.

Authors :Perelman RT , Church GM , Stein J

Published On :2025 Jul 18

Journal Article Preprint

Diphanes: cage-like compounds featuring two cavities.

Authors :Shen J , Zhang S

Published On :2025 Aug 21

Journal Article Review

Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.

Authors :Stein J , Ericsson M , Nofal M , Magni L , Aufmkolk S , McMillan RB , Breimann L , Herlihy CP , Lee SD , Willemin A , Wohlmann J , Arguedas-Jimenez L , Yin P , Pombo A , Church GM , Wu CT

Published On :2025 Aug 12

Journal Article

Construction of a Nomogram Model for Predicting Prognosis in Breast Cancer Patients Based on the Expression of THRSP and ACACA Proteins Tissues.

Authors :Wei B , Li F , Yan H , Shen J

Published On :2025

Journal Article

Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations.

Authors :Kobren SN , Moldovan MA , Reimers R , Traviglia D , Li X , Barnum D , Veit A , Corona RI , Carvalho Neto GV , Willett J , Berselli M , Ronchetti W , Nelson SF , Martinez-Agosto JA , Sherwood R , Krier J , Kohane IS , Undiagnosed Diseases Network , Sunyaev SR

Published On :2025 Aug 7

Journal Article

Academic Learning Profiles Across Disorders of KMT2 Gene Family: Superimposed and Distinct Features Across Kabuki, Wiedemann-Steiner and ODLURO Syndromes.

Authors :Ng R , Meier L , O'Donnell-Luria A , Harris J

Published On :2025 Nov

Journal Article