Publications | International Center for Genetic Disease at Harvard Medical School

Genome engineering.

Authors :Carr PA , Church GM

Published On :2009 Dec

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.

Authors :Mochida GH , Mahajnah M , Hill AD , Basel-Vanagaite L , Gleason D , Hill RS , Bodell A , Crosier M , Straussberg R , Walsh CA

Published On :2009 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Y-contacted high-performance n-type single-walled carbon nanotube field-effect transistors: scaling and comparison with Sc-contacted devices.

Authors :Ding L , Wang S , Zhang Z , Zeng Q , Wang Z , Pei T , Yang L , Liang X , Shen J , Chen Q , Cui R , Li Y , Peng LM

Published On :2009 Dec

Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't

SylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor syringolin A.

Authors :Imker HJ , Walsh CT , Wuest WM

Published On :2009 Dec 30

Journal Article Research Support, N.I.H., Extramural

A restricted spectrum of NRAS mutations causes Noonan syndrome.

Authors :Cirstea IC , Kutsche K , Dvorsky R , Gremer L , Carta C , Horn D , Roberts AE , Lepri F , Merbitz-Zahradnik T , König R , Kratz CP , Pantaleoni F , Dentici ML , Joshi VA , Kucherlapati RS , Mazzanti L , Mundlos S , Patton MA , Silengo MC , Rossi C , Zampino G , Digilio C , Stuppia L , Seemanova E , Pennacchio LA , Gelb BD , Dallapiccola B , Wittinghofer A , Ahmadian MR , Tartaglia M , Zenker M

Published On :2010 Jan

Case Reports Journal Article Research Support, Non-U.S. Gov't

Pro-inflammatory biomarkers during experimental gingivitis in patients with type 1 diabetes mellitus: a proof-of-concept study.

Authors :Salvi GE , Franco LM , Braun TM , Lee A , Rutger Persson G , Lang NP , Giannobile WV

Published On :2010 Jan

Comparative Study Journal Article Research Support, Non-U.S. Gov't

[Property studies on three-dimensional porous blended silk scaffolds].

Authors :Rao J , Shen J , Quan D , Xu Y

Published On :2009 Oct

English Abstract Journal Article

Cerebral blood flow characteristics and biometry in fetuses undergoing prenatal intervention for aortic stenosis with evolving hypoplastic left heart syndrome.

Authors :McElhinney DB , Benson CB , Brown DW , Wilkins-Haug LE , Marshall AC , Zaccagnini L , Tworetzky W

Published On :2010 Jan

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Thermal-lens study of photochemical reaction kinetics.

Authors :Astrath NG , Astrath FB , Shen J , Zhou J , Michaelian KH , Fairbridge C , Malacarne LC , Pedreira PR , Medina AN , Baesso ML

Published On :2009 Nov 15

Journal Article

Evolutionary trends of A(H1N1) influenza virus hemagglutinin since 1918.

Authors :Shen J , Ma J , Wang Q

Published On :2009 Nov 17

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.

Authors :van Rooij E , Quiat D , Johnson BA , Sutherland LB , Qi X , Richardson JA , Kelm RJ Jr , Olson EN

Published On :2009 Nov

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors :Imielinski M , Baldassano RN , Griffiths A , Russell RK , Annese V , Dubinsky M , Kugathasan S , Bradfield JP , Walters TD , Sleiman P , Kim CE , Muise A , Wang K , Glessner JT , Saeed S , Zhang H , Frackelton EC , Hou C , Flory JH , Otieno G , Chiavacci RM , Grundmeier R , Castro M , Latiano A , Dallapiccola B , Stempak J , Abrams DJ , Taylor K , McGovern D , Western Regional Alliance for Pediatric IBD , Silber G , Wrobel I , Quiros A , International IBD Genetics Consortium , Barrett JC , Hansoul S , Nicolae DL , Cho JH , Duerr RH , Rioux JD , Brant SR , Silverberg MS , Taylor KD , Barmuda MM , Bitton A , Dassopoulos T , Datta LW , Green T , Griffiths AM , Kistner EO , Murtha MT , Regueiro MD , Rotter JI , Schumm LP , Steinhart AH , Targan SR , Xavier RJ , NIDDK IBD Genetics Consortium , Libioulle C , Sandor C , Lathrop M , Belaiche J , Dewit O , Gut I , Heath S , Laukens D , Mni M , Rutgeerts P , Van Gossum A , Zelenika D , Franchimont D , Hugot JP , de Vos M , Vermeire S , Louis E , Belgian-French IBD Consortium , Wellcome Trust Case Control Consortium , Cardon LR , Anderson CA , Drummond H , Nimmo E , Ahmad T , Prescott NJ , Onnie CM , Fisher SA , Marchini J , Ghori J , Bumpstead S , Gwillam R , Tremelling M , Delukas P , Mansfield J , Jewell D , Satsangi J , Mathew CG , Parkes M , Georges M , Daly MJ , Heyman MB , Ferry GD , Kirschner B , Lee J , Essers J , Grand R , Stephens M , Levine A , Piccoli D , Van Limbergen J , Cucchiara S , Monos DS , Guthery SL , Denson L , Wilson DC , Grant SF , Daly M , Silverberg MS , Satsangi J , Hakonarson H

Published On :2009 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Generation of thiocillin variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.

Authors :Acker MG , Bowers AA , Walsh CT

Published On :2009 Dec 9

Journal Article Research Support, N.I.H., Extramural

A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.

Authors :Lee JH , Park IH , Gao Y , Li JB , Li Z , Daley GQ , Zhang K , Church GM

Published On :2009 Nov

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Meta-analysis: the efficacy and safety of monoclonal antibody targeted to epidermal growth factor receptor in the treatment of patients with metastatic colorectal cancer.

Authors :Nie F , Shen J , Tong JL , Xu XT , Zhu MM , Ran ZH

Published On :2009 Nov

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't