Publications | International Center for Genetic Disease at Harvard Medical School

The apical complex couples cell fate and cell survival to cerebral cortical development.

Authors :Kim S , Lehtinen MK , Sessa A , Zappaterra MW , Cho SH , Gonzalez D , Boggan B , Austin CA , Wijnholds J , Gambello MJ , Malicki J , LaMantia AS , Broccoli V , Walsh CA

Published On :2010 Apr 15

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Human allelic variation: perspective from protein function, structure, and evolution.

Authors :Jordan DM , Ramensky VE , Sunyaev SR

Published On :2010 Jun

Journal Article Research Support, N.I.H., Extramural Review

Membrane properties of neuron-like cells generated from adult human bone-marrow-derived mesenchymal stem cells.

Authors :Fox LE , Shen J , Ma K , Liu Q , Shi G , Pappas GD , Qu T , Cheng J

Published On :2010 Dec

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis.

Authors :Zhang W , Bolla ML , Kahne D , Walsh CT

Published On :2010 May 12

Journal Article Research Support, N.I.H., Extramural

A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion.

Authors :Sommer MO , Church GM , Dantas G

Published On :2010 Apr 13

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Coupled cluster with singles, doubles, and partial higher-order excitations based on the corresponding orbitals: the formulation and test applications for bond breaking processes.

Authors :Xu E , Shen J , Kou Z , Li S

Published On :2010 Apr 7

Journal Article

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Authors :Neale BM , Fagerness J , Reynolds R , Sobrin L , Parker M , Raychaudhuri S , Tan PL , Oh EC , Merriam JE , Souied E , Bernstein PS , Li B , Frederick JM , Zhang K , Brantley MA Jr , Lee AY , Zack DJ , Campochiaro B , Campochiaro P , Ripke S , Smith RT , Barile GR , Katsanis N , Allikmets R , Daly MJ , Seddon JM

Published On :2010 Apr 20

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Regulation of reactive oxygen species by p53: implications for nitric oxide-mediated apoptosis.

Authors :Popowich DA , Vavra AK , Walsh CP , Bhikhapurwala HA , Rossi NB , Jiang Q , Aalami OO , Kibbe MR

Published On :2010 Jun

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Personal genomes in progress: from the human genome project to the personal genome project.

Authors :Lunshof JE , Bobe J , Aach J , Angrist M , Thakuria JV , Vorhaus DB , Hoehe MR , Church GM

Published On :2010

Journal Article

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases.

Authors :Prisic S , Dankwa S , Schwartz D , Chou MF , Locasale JW , Kang CM , Bemis G , Church GM , Steen H , Husson RN

Published On :2010 Apr 20

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Authors :Silver DL , Watkins-Chow DE , Schreck KC , Pierfelice TJ , Larson DM , Burnetti AJ , Liaw HJ , Myung K , Walsh CA , Gaiano N , Pavan WJ

Published On :2010 May

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

Age is a strong risk factor for atrial fibrillation after pulmonary lobectomy.

Authors :Hollings DD , Higgins RS , Faber LP , Warren WH , Liptay MJ , Basu S , Kim AW

Published On :2010 Apr

Journal Article

Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT.

Authors :Marenco S , Savostyanova AA , van der Veen JW , Geramita M , Stern A , Barnett AS , Kolachana B , Radulescu E , Zhang F , Callicott JH , Straub RE , Shen J , Weinberger DR

Published On :2010 Jul

Journal Article Research Support, N.I.H., Extramural

Genetic malformations of the human frontal lobe.

Authors :Amrom D , Walsh CA

Published On :2010 Feb

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

A method and server for predicting damaging missense mutations.

Authors :Adzhubei IA , Schmidt S , Peshkin L , Ramensky VE , Gerasimova A , Bork P , Kondrashov AS , Sunyaev SR

Published On :2010 Apr

Letter Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't