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Three siderophores from one bacterial enzymatic assembly line.

Authors :Wuest WM , Sattely ES , Walsh CT
Published On :2009 Apr 15
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Human mutation rate associated with DNA replication timing.

Authors :Stamatoyannopoulos JA , Adzhubei I , Thurman RE , Kryukov GV , Mirkin SM , Sunyaev SR
Published On :2009 Apr
Journal Article Research Support, N.I.H., Extramural


Structural analysis of an open active site conformation of nonheme iron halogenase CytC3.

Authors :Wong C , Fujimori DG , Walsh CT , Drennan CL
Published On :2009 Apr 8
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.


Identification of pathogen and host-response markers correlated with periodontal disease.

Authors :Ramseier CA , Kinney JS , Herr AE , Braun T , Sugai JV , Shelburne CA , Rayburn LA , Tran HM , Singh AK , Giannobile WV
Published On :2009 Mar
Clinical Trial Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2.

Authors :Matthews ML , Krest CM , Barr EW , Vaillancourt FH , Walsh CT , Green MT , Krebs C , Bollinger JM
Published On :2009 May 26
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.


The role of the CD58 locus in multiple sclerosis.

Authors :De Jager PL , Baecher-Allan C , Maier LM , Arthur AT , Ottoboni L , Barcellos L , McCauley JL , Sawcer S , Goris A , Saarela J , Yelensky R , Price A , Leppa V , Patterson N , de Bakker PI , Tran D , Aubin C , Pobywajlo S , Rossin E , Hu X , Ashley CW , Choy E , Rioux JD , Pericak-Vance MA , Ivinson A , Booth DR , Stewart GJ , Palotie A , Peltonen L , Dubois B , Haines JL , Weiner HL , Compston A , Hauser SL , Daly MJ , Reich D , Oksenberg JR , Hafler DA
Published On :2009 Mar 31
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Chimeric AAV Cap sequences alter gene transduction.

Authors :Ward P , Walsh CE
Published On :2009 Apr 10
Journal Article Research Support, N.I.H., Extramural


Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS.

Authors :Kallio SP , Jakkula E , Purcell S , Suvela M , Koivisto K , Tienari PJ , Elovaara I , Pirttilä T , Reunanen M , Bronnikov D , Viander M , Meri S , Hillert J , Lundmark F , Harbo HF , Lorentzen AR , De Jager PL , Daly MJ , Hafler DA , Palotie A , Peltonen L , Saarela J
Published On :2009 May 1
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Tuberculosis drug resistance mutation database.

Authors :Sandgren A , Strong M , Muthukrishnan P , Weiner BK , Church GM , Murray MB
Published On :2009 Feb 10
Journal Article Research Support, Non-U.S. Gov't


Systemic MMP inhibition for periodontal wound repair: results of a multi-centre randomized-controlled clinical trial.

Authors :Gapski R , Hasturk H , Van Dyke TE , Oringer RJ , Wang S , Braun TM , Giannobile WV
Published On :2009 Feb
Journal Article Multicenter Study Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Power of deep, all-exon resequencing for discovery of human trait genes.

Authors :Kryukov GV , Shpunt A , Stamatoyannopoulos JA , Sunyaev SR
Published On :2009 Mar 10
Journal Article Research Support, N.I.H., Extramural


Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use.

Authors :Chang PC , Cirelli JA , Jin Q , Seol YJ , Sugai JV , D'Silva NJ , Danciu TE , Chandler LA , Sosnowski BA , Giannobile WV
Published On :2009 May
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Cascade reactions during coronafacic acid biosynthesis: elongation, cyclization, and functionalization during Cfa7-catalyzed condensation.

Authors :Strieter ER , Koglin A , Aron ZD , Walsh CT
Published On :2009 Feb 18
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

Authors :Myocardial Infarction Genetics Consortium , Kathiresan S , Voight BF , Purcell S , Musunuru K , Ardissino D , Mannucci PM , Anand S , Engert JC , Samani NJ , Schunkert H , Erdmann J , Reilly MP , Rader DJ , Morgan T , Spertus JA , Stoll M , Girelli D , McKeown PP , Patterson CC , Siscovick DS , O'Donnell CJ , Elosua R , Peltonen L , Salomaa V , Schwartz SM , Melander O , Altshuler D , Ardissino D , Merlini PA , Berzuini C , Bernardinelli L , Peyvandi F , Tubaro M , Celli P , Ferrario M , Fetiveau R , Marziliano N , Casari G , Galli M , Ribichini F , Rossi M , Bernardi F , Zonzin P , Piazza A , Mannucci PM , Schwartz SM , Siscovick DS , Yee J , Friedlander Y , Elosua R , Marrugat J , Lucas G , Subirana I , Sala J , Ramos R , Kathiresan S , Meigs JB , Williams G , Nathan DM , MacRae CA , O'Donnell CJ , Salomaa V , Havulinna AS , Peltonen L , Melander O , Berglund G , Voight BF , Kathiresan S , Hirschhorn JN , Asselta R , Duga S , Spreafico M , Musunuru K , Daly MJ , Purcell S , Voight BF , Purcell S , Nemesh J , Korn JM , McCarroll SA , Schwartz SM , Yee J , Kathiresan S , Lucas G , Subirana I , Elosua R , Surti A , Guiducci C , Gianniny L , Mirel D , Parkin M , Burtt N , Gabriel SB , Samani NJ , Thompson JR , Braund PS , Wright BJ , Balmforth AJ , Ball SG , Hall A , Wellcome Trust Case Control Consortium , Schunkert H , Erdmann J , Linsel-Nitschke P , Lieb W , Ziegler A , König I , Hengstenberg C , Fischer M , Stark K , Grosshennig A , Preuss M , Wichmann HE , Schreiber S , Schunkert H , Samani NJ , Erdmann J , Ouwehand W , Hengstenberg C , Deloukas P , Scholz M , Cambien F , Reilly MP , Li M , Chen Z , Wilensky R , Matthai W , Qasim A , Hakonarson HH , Devaney J , Burnett MS , Pichard AD , Kent KM , Satler L , Lindsay JM , Waksman R , Knouff CW , Waterworth DM , Walker MC , Mooser V , Epstein SE , Rader DJ , Scheffold T , Berger K , Stoll M , Huge A , Girelli D , Martinelli N , Olivieri O , Corrocher R , Morgan T , Spertus JA , McKeown P , Patterson CC , Schunkert H , Erdmann E , Linsel-Nitschke P , Lieb W , Ziegler A , König IR , Hengstenberg C , Fischer M , Stark K , Grosshennig A , Preuss M , Wichmann HE , Schreiber S , Hólm H , Thorleifsson G , Thorsteinsdottir U , Stefansson K , Engert JC , Do R , Xie C , Anand S , Kathiresan S , Ardissino D , Mannucci PM , Siscovick D , O'Donnell CJ , Samani NJ , Melander O , Elosua R , Peltonen L , Salomaa V , Schwartz SM , Altshuler D
Published On :2009 Mar
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't


Adaptive mutations in the JC virus protein capsid are associated with progressive multifocal leukoencephalopathy (PML).

Authors :Sunyaev SR , Lugovskoy A , Simon K , Gorelik L
Published On :2009 Feb
Journal Article Research Support, Non-U.S. Gov't